Results 101 to 110 of about 58,135 (307)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Case Report: A novel chemotherapy-free regimen combined with photodynamic therapy, target therapy, and immunotherapy in a geriatric male with huge recurrent scalp and facial angiosarcoma: a report of an extremely rare case and literature review

Frontiers in Immunology
Angiosarcomas are sporadic vascular neoplasms among the most aggressive subtypes of soft tissue sarcomas. In addition, vast and multiple recurrent superficial scalp and facial angiosarcomas are very complex and extremely difficult to manage.
Ewetse Paul Maswikiti, Zedong Feng, Zhenyu Yin, Fan Zhang, Lijuan He, Baohong Gu, Lin Xiang, Huixia Li, Caijuan Wang, Yang Yu, Bo Xu, Jize Wang, Jize Wang, Hao Chen, Hao Chen, Hao Chen   +15 more
doaj   +1 more source

Giant lipoma arising from deep lobe of the parotid gland

World Journal of Surgical Oncology, 2006
Background Lipomas are common benign soft tissue neoplasms but they are found very rarely in the deep lobe of parotid gland. Surgical intervention in these tumors is challenging because of the proximity of the facial nerve, and thus knowledge of the ...
Hsu Ying-Che, Chiang Feng-Yu, Chi Hung-Pin, Wu Che-Wei, Chan Leong-Perng, Kuo Wen-Rei   +5 more
doaj   +1 more source

Sinonasal inverted papilloma; recurrence, malignant transformation and risk factors [PDF]

, 2019
Sinonasal inverted papilloma is a rare benign epithelial tumor. Its three main clinical characteristics are the tendency of recurrence, the destructive ability of nearby structures and malignant transformation.
Ghindea, Teodora, Hainarosie, Razvan, Ionita, Irina, Mazilu, Laura, Meius, Alexandru, Nitipir, Cornelia, Pietrosanu, Catalina, Pituru, Silviu, Rusescu, Andreea, Timofte, Daniel   +9 more
core   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Intranasal melanoma treated with radiation therapy in three dogs [PDF]

, 2017
Three dogs were investigated for chronic unilateral nasal discharge. In all cases CT imaging showed an intranasal mass causing turbinate lysis and no evidence of metastasis.
Blackwood, L, Davies, O, Holmes, E, Lara-Garcia, A, Necova, S, Spencer, S, Taylor, A   +6 more
core   +4 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Intractable Facial Pain and Numb Chin due to Metastatic Esophageal Adenocarcinoma

Case Reports in Oncology, 2014
The etiologies of facial pain are innumerable, thus facial pain misdiagnosis and resultant mismanagement is common. Numb chin syndrome presents with hypoesthesia and/or anesthesia in the dermatomal distribution of the inferior alveolar or the mental ...
Foad Elahi, Whitney Luke, Fazel Elahi
doaj   +1 more source

Primary cerebellopontine angle melanocytoma: review. [PDF]

, 2012
Introduction Primary cerebellopontine angle melanocytomas (PCPAMs) are very rare. Their natural history and prognosis are not fully understood. We reviewed the literature and add a new case to analyze PCPAM's presentation, radiological features, and ...
Elashaal, R, Eljamel, S, Ironside, J, Phang, I   +3 more
core   +1 more source