Results 281 to 290 of about 263,524 (381)

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

Globotriaosylceramide Gb3 Influences Wound Healing and Scar Formation by Orchestrating Fibroblast Heterogeneity

Advanced Science, EarlyView.
In superficial second‐degree burn wounds, Gb3 turns on genes related to papillary cells through the FGF2 signaling pathway. This increases the ability of cells to break down fibrin and decreases fibrosis, which ultimately prevents scar formation in burn injuries.
Sujie Xie, Runzhi Huang, Weijin Qian, Xinran Ding, Wei Zhang, Yixu Li, Jianyu Lu, Hanlin Sun, Yifan Liu, Yuntao Yao, Bingnan Lu, Minjuan Wu, Zhaofan Xia, Shizhao Ji   +13 more
wiley   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source

Treating Hearing Loss: From Cochlear Implantation to Gene Therapy

Advanced Science, EarlyView.
Cochlear implantation is the primary treatment for deafness, restoring functional hearing in over a million people. Recently, gene therapy has enabled biological hearing restoration in a small number of patients with OTOF‐related mutations. This perspective evaluates both approaches, concluding that cochlear implants will remain the standard for most ...
Fan‐Gang Zeng, Jieyu Qi, Chen‐Chi Wu, Yilai Shu, Renjie Chai   +4 more
wiley   +1 more source

Bilateral Facial Nerve Palsy Revealing Diffuse Large B-Cell Lymphoma With Leptomeningeal Involvement. [PDF]

Cureus
Abu Laban AMB, Muhammad W, Hanbali N.
europepmc   +1 more source

Exploring the Causal Relationship Between Inflammatory Bowel Disease and Bell's Palsy Based on Inflammatory Proteins: A Mendelian Randomization Study. [PDF]

Brain Behav
Fan D, Wu W, Dai J, Chen Y, Lian Q, Zhao C, Que B, Qiu R.   +7 more
europepmc   +1 more source

Editorial: Craniofacial neuroscience. [PDF]

Front Neurol
Huff A, Katsura KA, Pitts T.
europepmc   +1 more source

Unveiling a rare cause of trigeminal neuralgia: Arteriovenous malformation diagnosed via MRI. [PDF]

Radiol Case Rep
Kadiri SE, Andour H, Qajia H, Izi Z, Jiddane M, Touarsa F.   +5 more
europepmc   +1 more source

Atypical Manifestation of Skull Base Osteomyelitis Secondary to Malignant Otitis Externa Following Radiotherapy: A Case Report. [PDF]

Cureus
Bouallou M, Essamhi Z, Sbai A, Benfadil D, Lachkar A, El Ayoubi El Idrissi F.   +5 more
europepmc   +1 more source

Long-term clinical outcomes after Lyme neuroborreliosis in children. [PDF]

BMC Pediatr
Bruinsma RA, Skogman BH, van Hensbroek MB, Vermeeren YM, Hovius JW, Zomer TP.   +5 more
europepmc   +1 more source