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Central Facial Nervous System Biomolecules Involved in Peripheral Facial Nerve Injury Responses and Potential Therapeutic Strategies [PDF]

Antioxidants, 2023
Peripheral facial nerve injury leads to changes in the expression of various neuroactive substances that affect nerve cell damage, survival, growth, and regeneration.
Jae-Min Lee, You Jung Choi, Myung Chul Yoo, Seung Geun Yeo   +3 more
doaj   +4 more sources

Expression of ChAT, Iba-1, and nNOS in the Central Nervous System following Facial Nerve Injury [PDF]

Antioxidants
Facial nerve injury can cause significant functional impairment, impacting both the peripheral and central nervous systems. The present study evaluated changes in facial motor function, numbers of cholinergic neurons and microglia, and nNOS levels in the
Jae Min Lee, Myung Chul Yoo, Yong Jun Kim, Sung Soo Kim, Seung Geun Yeo   +4 more
doaj   +4 more sources

Nicotinamide Adenine Dinucleotide Phosphate Oxidase 2 Expression and Effects of Alpha Lipoic Acid on Recovery in a Rat Model of Facial Nerve Injury [PDF]

Biomedicines, 2022
Background: NOX2 (nicotinamide adenine dinucleotide phosphate oxidase 2), which is upregulated by a variety of neurodegenerative factors, is neuroprotective and capable of reducing detrimental aspects of pathology following ischemic and traumatic brain ...
Myung Chul Yoo, In Yong Ryu, Jin Woo Choi, Jae Min Lee, Jae Yong Byun, Seung Geun Yeo   +5 more
doaj   +4 more sources

Porous Organic Materials in Tissue Engineering: Recent Advances and Applications for Severed Facial Nerve Injury Repair [PDF]

Molecules
The prevalence of facial nerve injury is substantial, and the restoration of its structure and function remains a significant challenge. Autologous nerve transplantation is a common treatment for severed facial nerve injury; however, it has great ...
Jingxuan Sun, Wenxin Cao, Shuang Pan, Lina He, Dongchao Ji, Nannan Zheng, Xiangyu Sun, Ranxu Wang, Yumei Niu   +8 more
doaj   +4 more sources

Traumatic facial nerve injury: A case of facial nerve avulsion at the cerebellopontine angle [PDF]

Radiology Case Reports, 2022
Post-traumatic facial nerve paralysis is a common disease, but intracranial facial nerve injury after blunt injury has rarely been reported. We report a case of facial nerve avulsion at the cerebellopontine angle.
Masumi Mizuki, MD, Fumio Suzuki, MD, PhD, Shiori Amemiya, MD, PhD, Hironobu Nishijima, MD, PhD, Yoshifumi Imai, MD, Osamu Abe, MD, PhD   +5 more
doaj   +2 more sources

Transcriptome analysis of molecular mechanisms underlying facial nerve injury repair in rats [PDF]

Neural Regeneration Research, 2021
Although the transcriptional alterations inside the facial nucleus after facial nerve injury have been well studied, the gene expression changes in the facial nerve trunk after injury are still unknown. In this study, we established an adult rat model of
Qian-Qian Cao, Shuo Li, Yan Lu, Di Wu, Wei Feng, Yong Shi, Lu-Ping Zhang   +6 more
doaj   +2 more sources

Facial Nerve Repair following Acute Nerve Injury

Archives of Plastic Surgery, 2022
Background Acute facial nerve iatrogenic or traumatic injury warrants rapid management with the goal of reestablishing nerve continuity within 72 hours.
Ehud Fliss, Ravit Yanko, Arik Zaretski, Roei Tulchinsky, Ehud Arad, Daniel J. Kedar, Dan M. Fliss, Eyal Gur   +7 more
doaj   +3 more sources

Research trends of facial nerve injury after cerebellopontine angle tumor: CiteSpace-based bibliometric analysis [PDF]

Frontiers in Neurology
BackgroundA bibliometric analysis was conducted to understand the current research status and trends in facial nerve injury after cerebellopontine angle (CPA) tumors to identify new perspectives for future research.MethodsCiteSpace was used to visualize ...
Xinxin Li, Bing Bai, Beibei Nie
doaj   +2 more sources

A multi-institutional machine learning algorithm for prognosticating facial nerve injury following microsurgical resection of vestibular schwannoma [PDF]

Scientific Reports
Vestibular schwannomas (VS) are the most common tumor of the skull base with available treatment options that carry a risk of iatrogenic injury to the facial nerve, which can significantly impact patients’ quality of life. As facial nerve outcomes remain
Sabrina M. Heman-Ackah, Rachel Blue, Alexandra E. Quimby, Hussein Abdallah, Elizabeth M. Sweeney, Daksh Chauhan, Tiffany Hwa, Jason Brant, Michael J. Ruckenstein, Douglas C. Bigelow, Christina Jackson, Georgios Zenonos, Paul Gardner, Selena E. Briggs, Yale Cohen, John Y. K. Lee   +15 more
doaj   +2 more sources

Exploring the relationship between the level of facial nerve injury and surgical outcome: Application of a new anatomical classification system in a limited cohort undergoing marginal mandibular nerve reconstruction [PDF]

JPRAS Open
Background: Reconstruction of the marginal mandibular nerve (MMN) is important for achieving optimal outcomes in the treatment of facial paralysis. However, the heterogeneity of injuries, ranging from extensive proximal facial nerve injuries to isolated ...
Villiam Vejbrink Kildal, Alex Okello Wamalwa, Ludvig Tidehag Walan, Andrés Rodriguez-Lorenzo   +3 more
doaj   +2 more sources