Results 71 to 80 of about 438,559 (288)

Current status and future directions of botulinum neurotoxins for targeting pain processing. [PDF]

, 2015
Current evidence suggests that botulinum neurotoxins (BoNTs) A1 and B1, given locally into peripheral tissues such as skin, muscles, and joints, alter nociceptive processing otherwise initiated by inflammation or nerve injury in animal models and humans.
Pellett, Sabine, Ramachandran, Roshni, Yaksh, Tony L   +2 more
core   +2 more sources

Critical Medical Ethics as an Approach to the Debate About Assisted Suicide by the Example of Germany

Bioethics, EarlyView.
ABSTRACT Recent literature has seen a growing endorsement of the so‐called autonomy‐only approach to assisted dying, which rejects suffering as a necessary criterion for access. Proponents argue that this model is most suitable to safeguard individuals against value‐based judgments of healthcare professionals about whether their lives are still worth ...
Meike Gerber
wiley   +1 more source

Pathogenesis, Diagnosis, and Management of Trigeminal Neuralgia: A Narrative Review

Journal of Clinical Medicine
Trigeminal neuralgia (TN) is an excruciating neurological disorder characterized by intense, stimulus-induced, and transient facial stabbing pain. The classification of TN has changed as a result of new discoveries in the last decade regarding its ...
Yao Liu, E. Tanaka
semanticscholar   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Avaliação psicológica e enfrentamento na neuralgia trigeminal e disfunção temporomandibular [PDF]

, 2008
OBJECTIVE: To determine the psychological aspects of orofacial pain in trigeminal neuralgia (TN) and temporomandibular disorder (TMD), and associated factors of coping as limitations in daily activities and feelings about the treatment and about the pain.
CASTRO, Adriana Ronchetti de, PERISSINOTTI, Dirce Maria Navas, SIQUEIRA, José Tadeu Tesseroli de, SIQUEIRA, Silvia Regina Dowgan Tesseroli de   +3 more
core   +2 more sources

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

A case report of Parry Romberg Syndrome initially presenting as periodontitis [PDF]

, 2018
Parry Romberg Syndrome (PRS) is a rare disorder of progressive hemifacial atrophy, involving soft tissues, fat and occasionally bone. It can co-exist with presentations of Morphea.
Bramley, Duymaz, El-Kehdy, Fayad, Gorlin, Grippaudo, Lehman, Lewkonia, Mazzeo, Miller, Saraf, Stone, Sándor, Tollefson, Yu-Feng   +14 more
core   +1 more source

Goitre and Iodine Deficiency in Europe [PDF]

, 1985
The prevalence of endemic iodine-deficiency goitre in Europe has been reduced in many areas by the introduction of iodination programmes. Recent reports, however, show that goitre remains a significant problem and that its prevalence has not decreased in
Beckers, C., Bürgi, H., Escobar del Rey, F., Gembicki, M., Koutras, D. A., Lamberg, B. A., Langer, P., Lazarus, J. H., Querido, A., Scriba, Peter Christian, Thilly, C., Vigneri, R.   +11 more
core   +4 more sources

Elimination of pain improves specificity of clinical diagnostic criteria for adult chronic rhinosinusitis [PDF]

, 2017
Objective Determine whether the elimination of pain improves accuracy of clinical diagnostic criteria for adult chronic rhinosinusitis. Study Design Retrospective cohort study.
DiNardo, Laurence J., Hirsch, Scott D., Reiter, Evan R., Schuman, Theodore A., Wan, Wen   +4 more
core   +2 more sources

The Enigma of a Traumatic Neuroma: A Case of Nerve Proliferation Without Documented History of Trauma

Clinical Case Reports, Volume 14, Issue 2, February 2026.
Intraoperative photograph showing the reflection of full thickness flap over the body of mandible exposing the lesion and specimen following excisional biopsy. ABSTRACT In the differential diagnosis of nerve‐related lesions, even when there is no documented trauma, this case emphasizes the significance of taking traumatic neuroma into account.
Shristi Maharjan, Bibek Kattel, Niroj Khanal, Sabin Baniya, Anjani Kumar Yadav, Pradeep Acharya, Ashok Dongol, Mehul Rajesh Jaisani   +7 more
wiley   +1 more source