Results 51 to 60 of about 502,689 (316)

Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry

open access: yesChemMedChem, EarlyView.
This review highlights the rationale behind multitarget drug design as a promising approach to address diseases with complex etiologies. By combining pharmacophore features from different single‐target drugs, multitarget compounds can interact with multiple biological targets simultaneously.
Sadık Hüseyin Cemali   +7 more
wiley   +1 more source

Societal Identification of Facial Paralysis and Paralysis Location

open access: yesJAMA Facial Plastic Surgery, 2018
Importance When able to identify facial paralysis, members of society regard individuals with facial paralysis differently. They perceive a decrease in attractiveness, more negative affect, and lower quality of life. However, the ability of lay people in
Peiyi Su   +7 more
semanticscholar   +1 more source

Itinerant curriculum theory: People's theory against the field's epistemicidal ethos

open access: yesThe Curriculum Journal, EarlyView.
Abstract The field of curriculum studies suffers from a glaring theoretical impasse. Much of this impasse has been rightly attributed to the triumphalism of the neoliberal wave that has massacred the educational hemisphere with policies and practices that reduce pedagogy to an instrumentalist praxis directly associated with the thirsty desires and ...
João M. Paraskeva
wiley   +1 more source

Exploring Political Polarization Between Opponents and Supporters of Ruling Parties Following the 2019 Lebanese Uprising

open access: yesEuropean Journal of Social Psychology, EarlyView.
ABSTRACT The 17 October 2019 uprising in Lebanon marked a pivotal period of economic crisis and discontent with the ruling elite. We examined social cohesion post‐uprising by exploring political polarization between “anti‐ruling parties” citizens and “partisan/unaligned” citizens, in two surveys with a community sample (Study 1, N = 357) and a ...
Mortada Al‐Amine   +3 more
wiley   +1 more source

Anti‐Inflammatory Effects of Flavonoids in Otitis Media: A Systematic Review of Pre‐Clinical Evidence

open access: yesFood Frontiers, EarlyView.
Otitis media (OM) is a middle ear infection driven by chronic inflammation, leading to tissue damage and complications such as cholesteatoma. Flavonoids, a class of polyphenols with anti‐inflammatory properties, suppress key inflammatory mediators, reducing neutrophilic infiltration and mucosal thickening. These findings suggest flavonoids as potential
Madiha Ajaz   +3 more
wiley   +1 more source

Deciphering of nutritional profile, therapeutic potential, and networking of bioactive compounds of Moringa oleifera: A comprehensive review

open access: yesFood Biomacromolecules, EarlyView.
The graphical abstract signifies the nutritional profile of various parts of the Moringa oleifera plant, including dried leaves, fresh leaves, leaf powder, seeds, and pods; along with it’s bioactive substance and protein profiling of aqueous concentrates derived from the fruit, seed, and leaf.
Rajesh Kumar   +5 more
wiley   +1 more source

Conversion Surgery After Administration of a TRK Inhibitor for Unresectable Parotid Gland Secretory Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The NTRK fusion gene is detected in most salivary gland secretory carcinomas. While tropomyosin receptor kinase (TRK) inhibitors are used for various solid tumors with the fusion gene, there are no reports regarding TRK inhibitor use for unresectable parotid gland carcinomas that subsequently shrink and become resectable.
Arisa Nagano   +11 more
wiley   +1 more source

Late Toxicity and Long‐Term Quality of Life in Survivors of Cancer of the Major Salivary Glands More Than 5 Years After Diagnosis: A Multi‐National Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Because salivary gland cancers (SGC) are rare and include different tumor subtypes, data on their long‐term quality of life and late toxicities are sparse. Methods Multi‐national study including SGC survivors more than 5 years after diagnosis.
Susanne Singer   +26 more
wiley   +1 more source

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