Results 81 to 90 of about 38,302 (261)

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

open access: yesiMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu   +7 more
wiley   +1 more source

Taking Jobs and Doing Harm

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT In popular discourse and in the philosophical literature there is almost no reflection on the morality of doing harm in the context of doing one's job. To the contrary, workers are valorised simply for having a job, and typically individual workers are spared from blame, even when they cause significant harm as part of their job.
Theron Pummer, Benjamin Sachs‐Cobbe
wiley   +1 more source

When Does Top Management Team Diversity Matter in Large Organizations?

open access: yesJournal of Organizational Behavior, EarlyView.
ABSTRACT Top management teams (TMTs) drive strategic leadership, but there is little clarity on when the composition of these upper echelons most impacts organization performance. Drawing from the categorization‐elaboration model, we study an 18‐year sample of approximately 4500 organizations and over 32 000 executives and find a positive relationship ...
Frances Fabian   +2 more
wiley   +1 more source

Sustained seizure freedom with fenfluramine for refractory epilepsy due to 7q32‐q34 deletion syndrome

open access: yes
Epileptic Disorders, EarlyView.
Divya Veerapaneni   +2 more
wiley   +1 more source

Diagnostic Delay of Unilateral Facial Paralysis Caused by Occult Malignancy: A Scoping Review

open access: yesThe Laryngoscope, EarlyView.
This scoping review of 27 studies (66 patients) characterizes unilateral facial paralysis caused by occult malignancy, a rare entity marked by a mean diagnostic delay of 21 months and initially negative imaging in 89% of cases. Progressive paralysis, lack of recovery, trigeminal or additional cranial nerve involvement, and a history of regional skin ...
Kai C. Kokesh   +4 more
wiley   +1 more source

Taste Dysfunction and Bell's Palsy: A Scoping Review

open access: yesThe Laryngoscope, EarlyView.
Taste dysfunction is a well‐recognized but inconsistently reported symptom in Bell's palsy. This scoping review found that taste dysfunction is prevalent in these patients, often precedes facial weakness, and commonly improves within 6 months. Standardized, longitudinal studies employing validated psychophysical measures are needed to clarify the ...
Sherina R. Thomas   +2 more
wiley   +1 more source

Dynamic and Objective Quantification of Facial Nerve Palsy Using Smartphone‐Based 3D Facial Geometry

open access: yesThe Laryngoscope, EarlyView.
This prospective study evaluated smartphone‐captured high‐resolution 3D facial geometry in 99 patients with unilateral facial nerve palsy across 207 visits and 12 healthy volunteers. Dynamic motion features combined with machine learning accurately estimated signed continuous House–Brackmann severity and identified clinically significant palsy ...
Koki Hasebe   +9 more
wiley   +1 more source

Prevalence of Facial Paralysis After Surgical Treatment of Malignant Tumors of the Parotid Gland: A Systematic Review

open access: yesPesquisa Brasileira em Odontopediatria e Clínica Integrada
Objective: To estimate the prevalence of facial paralysis in patients with malignant parotid tumors who underwent parotidectomy. Material and Methods: The method employed was a systematic review, with a search conducted in the following databases: PubMed,
Nathália Cunha Lima D’Assunção   +3 more
doaj  

Impact of Age and Nerve Impairment Interaction on Bell's Palsy Prognosis

open access: yesThe Laryngoscope, EarlyView.
This study investigated the prognostic impact of the interaction between aging and nerve impairment severity in 181 patients with Bell's palsy. Although age alone was not an independent predictor, the interaction between older age (≥ 65 years) and a Nerve Excitability Test threshold difference (≥ 3.5 mA) significantly increased the risk of incomplete ...
Hiroyuki Yamada   +7 more
wiley   +1 more source

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