Results 71 to 80 of about 259,377 (305)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Trade Facilitation in Developing Countries [PDF]

Measures to actively facilitate trade are increasingly seen as essential to assist developing countries in expanding trade and benefiting from globalisation.
Oliver Morrissey, Evious Zgovu, Chris Milner   +2 more
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

A Comparative Analysis of Trade Facilitation in Selected Regional and Bilateral Trade Agreement [PDF]

This study compared the treatment of trade facilitation in four selected regional trade agreements, AFTA, APEC, SAFRA and PACER, and in one bilateral free trade agreement being the Australia-Singapore Free Trade Agreement (ASFTA), with a view to ...
Institute for International Trade
core  

Exploring facilitation strategies to support socially shared regulation in a problem-based learning game

Educational Technology & Society
Successful problem-based learning (PBL) often requires students to collectively regulate their learning processes as a group and engage in socially shared regulation of learning (SSRL). This paper focuses on how facilitators supported SSRL in the context
Chen Feng, Haesol Bae, Krista Glazewski, Cindy E. Hmelo-Silver, Thomas A. Brush, Bradford W. Mott, Seung Y. Lee, James C. Lester   +7 more
doaj   +1 more source

Facilitating Facilitators: Enhancing PBL through a Structured Facilitator Development Program

Interdisciplinary Journal of Problem-Based Learning, 2015
With increasing adoption of the problem-based learning (PBL) model, creative approaches to enhancing facilitator training and optimizing resources to maintain effective learning in small groups is essential. We describe a theoretical framework for the development of a PBL facilitator training program that uses the constructivist approach as the program’
Salinitri, Francine D., Wilhelm, Sheila M., Crabtree, Brian L.   +2 more
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Implementing a WTO agreement on trade facilitation : what makes sense ? [PDF]

Contrary to the prevailing view that the Doha negotiations have achieved little, the authors find that on trade facilitation much progress has been made.
Finger, J. Michael, Wilson, John S.
core  

Differential effects of location and object overlap on new learning

Frontiers in Cognition
IntroductionOverlap with prior experience facilitates learning in some cases while hindering it in others. As facilitation and interference are typically studied in separate lines of research, using distinct paradigms, it is unclear what key factors ...
Benjamin Chaloupka, Benjamin Chaloupka, Dagmar Zeithamova, Dagmar Zeithamova   +3 more
doaj   +1 more source

Facilitating facilitators to facilitate, in problem or enquiry based learning sessions

Journal of Problem Based Learning in Higher Education, 2014
Problem based learning (PBL) has been used in dental education over the past 20 years and uses a patient case scenario to stimulate learning in a small group setting, where a trained facilitator does not teach but guides the group to bring about deep contextualized learning, to be empathetic to each other and to encourage fair and equitable ...
openaire   +2 more sources