Results 191 to 200 of about 62,310 (257)

How and in what circumstances does facilitation work for residential aged care staff in the implementation of palliative care interventions? A realist review. [PDF]

Palliat Med
Lock K, Zhi Yan Lee L, Goh A, Gerber K, Lim WK, Tropea J, Astbury B.   +6 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Professionals on the Front Line: A Mixed-methods Study of Perceived Needs, Challenges, and Emotional Well-being in Intimate Partner Violence Intervention Programs. [PDF]

Psychosoc Interv
Pérez-Sabater R, Expósito-Álvarez C, Roldán-Pardo M, Conchell R, Pérez A, Terreros E, Vargas V, Villagrán AM, Lila M.   +8 more
europepmc   +1 more source

Optimizing peer review rounds in radiation oncology: a scoping review. [PDF]

Front Oncol
Zhang J, Bayley C, Vaska M, Lee SL.
europepmc   +1 more source

Economic cost of strategic implementation approaches to increase uptake of digital therapeutics for substance use disorders in a large integrated health system. [PDF]

PLOS Digit Health
Wong ES, Dorsey CN, Beatty TC, Bobb JF, Stefanik-Guizlo K, Key DL, Ramaprasan A, Idu AE, Fortney JC, Mogk J, Palazzo L, Caldeiro RM, King D, McWethy AG, Glass JE.   +14 more
europepmc   +1 more source

Implementation fidelity of Ethiopia's Malaria test-and-treat guideline amid a resurgence in Amhara Region: A mixed-methods study. [PDF]

PLoS One
Lake MW, Gelaye KA, Asemahagn MA, Muchie KF, Engedaw HA, Yenesew MA.   +5 more
europepmc   +1 more source

Coffee Chats: A Virtual Peer Support Model Developed by and for Caregivers Concerned About the Mental Health of Neurodivergent Adults. [PDF]

J Patient Exp
Dawthorne N, Fogle AA, Goldsmith L, Lunsky Y, Lake J.   +4 more
europepmc   +1 more source

Voices of learners: a qualitative exploration of nursing students' satisfaction with simulation-based basic life support training. [PDF]

BMC Med Educ
S B, N BD, C HSJ, Lakshmi L.
europepmc   +1 more source