Microengineered Gradient Hydrogels for Mechanobiology
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong +4 more
wiley +1 more source
Extensions to emergency vehicle location models [PDF]
This paper is concerned with extending models for the Maximal Covering Location Problem in two ways. First, the usual 0-1 coverage definition is replaced by the probability of covering a demand within the target time.
Rand, G K, Alsalloum, O I
core
Improvements and comparison of heuristics for solving the uncapacitated multisource Weber problem
Copyright @ 2000 INFORMSThe multisource Weber problem is to locate simultaneously m facilities in the Euclidean plane to minimize the total transportation cost for satisfying the demand of n fixed users, each supplied from its closest facility.
Taillard, ED +3 more
core +1 more source
A Fast Algorithm for Facility Location Problem
In this paper, we present an approximation algorithm achieving approximation guarantee of 2 for the classical uncapacitated facility location problem. The distinguishing feature of our designed algorithm is the overall low running time of , where , and are the number of cities and facilities.
openaire +1 more source
Natural Biomaterials for Osteochondral Repair: From Source to Strategy
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu +5 more
wiley +1 more source
Facility layout design with random demand and capacitated machines [PDF]
We consider the facility layout problem with machine capacities (and hence multiple machines of each type) and random demand. We develop a very efficient heuristic allowing us to find good solutions to the stochastic case whenever good solutions can be ...
Wallace, Stein W., Zhao, Yifei
core
Heuristic Methods Based on MINLP Formulation for Reliable Capacitated Facility Location Problems
This paper addresses a reliable facility location problem with considering facility capacity constraints. In reliable facility location problem some facilities may become unavailable from time to time.
Mohammad Rohaninejad +2 more
doaj
Cuckoo search via Levy flights applied to uncapacitated facility location problem
Facility location problem (FLP) is a mathematical way to optimally locate facilities within a set of candidates to satisfy the requirements of a given set of clients.
Armacheska Mesa +3 more
doaj +1 more source
Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno +16 more
wiley +1 more source
Vertiport Infrastructure Location Optimization for Equitable Access to Urban Air Mobility
Urban air mobility (UAM) has recently emerged as a promising new transportation mode, with various potential use cases. Facility location problems are well studied and of significant importance for various transportation modes.
Vasileios Volakakis, Hani S. Mahmassani
doaj +1 more source

