Results 51 to 60 of about 1,109,525 (329)

Single-facility huff location problems on networks [PDF]

open access: yesAnnals of Operations Research, 2013
Huff location problems have been extensively analyzed within the field of competitive continuous location. In this work, two Huff location models on networks are addressed, by considering that users go directly to the facility or they visit the facility in their way to a destination.
Nogales Gómez, Amaya   +3 more
openaire   +6 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

A Continuous Approximation Approach Based on Regular Hexagon Partition for the Facility Location Problem under Disruptions Risk

open access: yesComplexity, 2019
Today’s business environment is complex, dynamic, and uncertain which makes a supply chain facility increasingly vulnerable to disruption from various risk accidents as one of the main threats to the whole supply chain’s operation.
Jiguang Wang, Yucai Wu
doaj   +1 more source

Two traveling salesman facility location problems [PDF]

open access: yes, 1988
Includes bibliographical references.Work partially supported by the National Science Foundation.

core  

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Fractional location problems [PDF]

open access: yes, 1997
In this paper we analyze some variants of the classical uncapacitated facility location problem with a ratio as an objective function. Using basic concepts and results of fractional programming, we identify a class of one-level fractional location ...
Barros, A.I. (Ana)   +2 more
core   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick   +14 more
wiley   +1 more source

An analysis of the impact of demand aggregation on the solution quality for facility location problems

open access: yesTransportes, 2023
Inspired by real-world applications, this paper studies the impact on the quality of solutions for facility location problems in which demand points are aggregated to reduce the size of the underlying mathematical formulation.
Renata Akemi Marçal Imai   +2 more
doaj   +1 more source

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