Results 91 to 100 of about 1,220,408 (258)
CHIMIA, 2001 This essay describes an approach facing some of the challenges of glycoscience, concentrating on the relation between structure and reactivity. This has resulted in new methods, precursors of carbohydrate-derived reactive intermediates, analysis
Andrea Vaselia
doaj
A new design concept of actively cooled plasma-facing units for the divertors of fusion reactors
Nuclear Materials and EnergyThis paper sketches a new divertor design concept that solves most of the issues already identified with the actual ITER design, especially in what concerns transient heat loading. It resists ELM heat loads better than the present ITER design.
J.P. Gunn +3 more
doaj +1 more source
[sic], 2014 Timely, provocative, and theoretically sophisticated, the essays comprising In the Face of Crises: Anglophone Literature in the Postmodern World situate their work amid several critical global concerns: the devastation wreaked by global capitalism ...
Moira Baker
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Facing the Music: Shaping music education from a global perspective
, 2010 Facing the Music makes a powerful case for the crucial role of world music in shaping rich and diverse learning environments for the 21st century. Author Huib Schippers investigates practices and ideas that have grown from the rise of 'world music ...
Schippers, H
core
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Creating Transformative Spaces in Education: Facing Humanity, Facing Violence
Philosophical Inquiry in Education, 2015 This paper considers the difficulties that accompany projects in education variously configured around a multicultural or intercultural label, particularly when they are built upon, for example, idealised conceptions of humanity, notions of the common ...
Sharon Todd
doaj
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Challenges Facing Farmers: A report into upland farming and farming families in Teesdale [PDF]
, 2012 Ensuring the viability of upland farmers, so that they can continue as producers of food and stewards of these valuable natural resources has been an ongoing concern for policy-makers, public bodies, businesses, charities, rural communities and ...
core +1 more source