Results 41 to 50 of about 1,220,408 (258)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Liquid surfaces for fusion plasma facing components—A critical review. Part I: Physics and PSI
Nuclear Materials and Energy, 2016 This review of the potential of robust plasma facing components (PFCs) with liquid surfaces for applications in future D/T fusion device summarizes the critical issues for liquid surfaces and research being done worldwide in confinement facilities, and ...
R.E. Nygren, F.L. Tabarés
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
INVOLUTE CHAIN TRANSMISSION SPROCKETS
Advanced Engineering Research, 2013 A method of manufacturing involute sprocket by a standard cutter for the toothed chain is suggested. The application of involute sprockets compared with straight and standard tooth profiles has a number of advantages: noise abatement under operation ...
Sergey Borisovich Berezhnoy +2 more
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Exploring the key socio-economic challenges facing youth refugees in the Western Cape [PDF]
, 2012 Includes abstract.Includes bibliographical references.This study explored the key socio-economic challenges facing youth refugees in the Western Cape. The study was carried out on a purposive sample of twelve youth refugees.
Shawa, Elizabeth HL
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Facing the challenges of water governance
, 2018 Published: 3 September 2018Access to water is one of the most pressing global issues of the twenty-first century, particularly when set against the background of a rapidly growing global population.
core +1 more source
Enhancing fluidic oscillator performance using multiple backward-facing steps in the mixing chamber
Journal of King Saud University: Engineering SciencesThe increase in FO frequency due to the use of BFS is accompanied by an increase in pressure losses. The study was conducted using the URANS governing equation and the SST k-ω turbulence model.
Waridho Iskandar +5 more
doaj +1 more source