Results 41 to 50 of about 21,871,150 (353)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Understanding youth and young adult cannabis use in Canada post-legalization: a scoping review on a public health issue

open access: yesSubstance Abuse Treatment, Prevention, and Policy
Background Canada legalized recreational cannabis in 2018, and one of the primary objectives of the Cannabis Act was to protect youth by reducing their access to cannabis and providing public education.
Toula Kourgiantakis   +8 more
doaj   +1 more source

Effect of Plant Protein on Blood Lipids: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundThere is a heightened interest in plant‐based diets for cardiovascular disease prevention. Although plant protein is thought to mediate such prevention through modifying blood lipids, the effect of plant protein in specific substitution for ...
Siying S. Li   +10 more
doaj   +1 more source

Local Out-Tournaments with Upset Tournament Strong Components I: Full and Equal {0,1}-Matrix Ranks [PDF]

open access: yes, 2010
A digraph D is a local out-tournament if the outset of every vertex is a tournament. Here, we use local out-tournaments, whose strong components are upset tournaments, to explore the corresponding ranks of the adjacency matrices.
Derby, Jason M.   +2 more
core   +1 more source

Self-Similar Factor Approximants [PDF]

open access: yes, 2002
The problem of reconstructing functions from their asymptotic expansions in powers of a small variable is addressed by deriving a novel type of approximants.
A. Okopińska   +41 more
core   +2 more sources

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

FGF Signaling Pathway: A Key Regulator of Stem Cell Pluripotency

open access: yesFrontiers in Cell and Developmental Biology, 2020
Pluripotent stem cells (PSCs) isolated in vitro from embryonic stem cells (ESCs), induced PSC (iPSC) and also post-implantation epiblast-derived stem cells (EpiSCs) are known for their two unique characteristics: the ability to give rise to all somatic ...
Majid Mossahebi-Mohammadi   +4 more
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Reducing the harms of cannabis use in youth post-legalization: insights from Ontario youth, parents, and service providers

open access: yesHarm Reduction Journal
Background Canada has one of the highest prevalence of cannabis use globally, particularly among young adults aged 20–24 (50%) and youth aged 16–19 (37%).
Toula Kourgiantakis   +8 more
doaj   +1 more source

Characteristics of child welfare investigations reported by healthcare professionals in Ontario: secondary analysis of a regional database

open access: yesBMJ Paediatrics Open, 2021
Objectives This study examines the characteristics and outcomes of child welfare investigations reported by hospital-based and community-based healthcare professionals.Methods A sample of 7590 child maltreatment-related investigations from the Ontario ...
Barbara Fallon   +7 more
doaj   +1 more source

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