Results 151 to 160 of about 5,158,228 (296)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Algebraic Approach to Maximum Likelihood Factor Analysis. [PDF]
PsychometrikaFukasaku R +3 more
europepmc +1 more source
Infectious keratoconjunctivitis in European bison (Bison bonasus) in Poland: risk factors, epidemiology and anatomopathological changes with analysis of potential role of Thelazia nematodes in the disease development [PDF]
Katarzyna Filip-Hutsch +7 more
openalex +1 more source
Social contextual factors contributing to child and adolescent labor: an ecological analysis [PDF]
, 2011 Vilma Sousa Santana, Martha Itaparica
openalex +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Validation of the Professionalism of Healthcare Professionals Scale : A Confirmatory Factor Analysis. [PDF]
Yonago Acta MedMinamimae N +4 more
europepmc +1 more source