Results 231 to 240 of about 5,158,228 (296)

FACTOR ANALYSIS ON SPATIAL PATTERNS OF POPULATION CHANGE AND DESIGN OF COMPACT CITY SCENARIOS IN PROVINCIAL MIDDLE SIZE CITY

, 2018
Hisanori Yagi, Kyohei Kajie, Shota TAMURA, Takahiro Tanaka, Daisaku NISHINA   +4 more
openalex   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Risk Factor Analysis of CRE Infections at Different Anatomical Sites in ICU Patients. [PDF]

Antibiotics (Basel)
Tang G, Song H, Mao L, Yan S, Tian L, Jian C, Chen Z, Sun Z, Wang Y.   +8 more
europepmc   +1 more source

Analysis of Malaria Incidence based on Behavioral Factors in the Islands

, 2018
Irma Muslimin, Andi Agus Salim
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Artificial intelligence and academic writing questionnaire (AI-AWQ): development and validation among medical students' experiences using exploratory factor analysis. [PDF]

BMC Med Educ
Khojasteh L, Karimian Z, Nasiri E, Kafipour R, Farahmandi AY.   +4 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The Risk Factor Analysis of Gallbladder Gangrene in Acute Acalculous Cholecystitis: A Single-Center Retrospective Study. [PDF]

Gastroenterol Res Pract
Zheng JL, Liu SQ, Liu YH, Dai GH, Feng HG, Tan HY.   +5 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Prevalence and Risk Factor Analysis of Feline Blood-Borne Pathogens in Bangkok and Vicinities, Thailand. [PDF]

Vet Med Int
Rodmanee N, Umnuayyonvaree D, Kaewthamasorn M, Hunprasit V, Ritthikulprasert S.   +4 more
europepmc   +1 more source