Results 51 to 60 of about 13,519,209 (293)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Empirical Analysis and Control Strategies of Grain Supply Chain Risk Assessment in Guangdong Province

open access: yesGuangdong nongye kexue
【Objective】As the largest grain sales area in China, the grain security issue of Guangdong Province occupies a special important position in the overall situation of national grain security.
Ting ZHANG   +3 more
doaj   +1 more source

Combining Functional Data Registration and Factor Analysis

open access: yes, 2015
We extend the definition of functional data registration to encompass a larger class of registered functions. In contrast to traditional registration models, we allow for registered functions that have more than one primary direction of variation.
Earls, Cecilia, Hooker, Giles
core   +2 more sources

The Vector Meson Form Factor Analysis in Light-Front Dynamics [PDF]

open access: yes, 2002
We study the form factors of vector mesons using a covariant fermion field theory model in $(3+1)$ dimensions. Performing a light-front calculation in the $q^+ =0$ frame in parallel with a manifestly covariant calculation, we note the existence of a ...
B.D. Keister   +25 more
core   +3 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Scalable Group Level Probabilistic Sparse Factor Analysis

open access: yes, 2016
Many data-driven approaches exist to extract neural representations of functional magnetic resonance imaging (fMRI) data, but most of them lack a proper probabilistic formulation.
Eriksen, Casper T.   +8 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Path Analysis on the Psychosocial Factors Affecting Anxiety and Delivery Pain [PDF]

open access: yes, 2018
Background: Previous studies have shown a high prevalence of psychiatric illness in pregnant women. A large body of research exists on the adverse outcomes of maternal psychological ill health, most notably depression and anxiety during pregnancy ...
Murti, B. (Bhisma)   +2 more
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Construction, Validation, and Factor Analysis of a Questionnaire on Practical Commitment to the Inner Etiquettes of Prayer (Salat) Based on Islamic Sources [PDF]

open access: yesاخلاق وحیانی
Practical adherence to the inner etiquettes of prayer is a central concept in Islam, extensively emphasized in the Qur'an and Hadith due to its profound impact on various aspects of human life.
Hamed Ranjbar, Ahad Omidi
doaj   +1 more source

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