Results 181 to 190 of about 4,658,239 (268)

Tailored collagen binding of albumin-fused hyperactive coagulation factor IX dictates in vivo distribution and functional properties. [PDF]

Nat Commun
Aaen KH, Testa MF, Nilsen J, Tarantino R, Canepari C, Benedusi M, Benjakul S, Nyquist-Andersen M, Herigstad ML, Cantore A, Valacchi G, Sandlie I, Bernardi F, Pinotti M, Branchini A, Andersen JT.   +15 more
europepmc   +1 more source

Microvascular Damage Is Associated With Carotid Wall Structural Changes in Systemic Sclerosis: A Capillaroscopy and Ultrasound‐Based Observational Study

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli, Luca Clerici, Francesco Lapia, Giusy C. Moltisanti, Eleonora Zaccara, Greta Pellegrino, Daniela Bompane, Francesca Capelli, Letizia Ferrami, Laura Castelnovo, Antonio Tamburello, Maria Sole Chimenti, Paola Faggioli, Antonino Mazzone   +13 more
wiley   +1 more source

A precision gene-engineered B cell medicine producing sustained levels of active factor IX for hemophilia B therapy. [PDF]

Mol Ther
Liu H, Singh S, Mullen TJ, Bullock C, Keegan S, Patterson T, Thakur S, Lundberg A, Shenker S, Couto R, Yadav C, Dastagir S, Li L, Bainter W, Liberzon E, Malloy CR, Lazzarotto CR, Ohsumi TK, Chilakala S, Chen HM, Kshirsagar R, Hohmann AF, Arlauckas SP, Lazorchak A, Scull C, Morgan RA.   +25 more
europepmc   +1 more source

Establishment of the WHO 2nd International Standard Factor V, plasma (16/374) : communication from the SSC of the ISTH

, 2019
Peyvandi, F., Jeanpierre, E., Young, B., Zadro, R., Gottschalk, N., Thelwell, Craig, Ovanesov, M., Kaar, W., Kitchen, S., Hubbard, Anthony R., Gebauer, R., Bevan, S., Grimaux, M., Doyle, M., Novembrino, C., Baker, P., Parunov, L., Stroobants, A., Bryngelhed, P., Riddell, A., Grenet, J., Rosenkranz, S., Rigano, J., Liang, Y., Surov, S., Jung, K., Mackie, I, Maes, Marie-Berthe, Hunfeld, A., Aime, C., Park, S., Kusch, M., Lawrence, C., Rigsby, Peter, Foulon, D., Teramura, G., Johnson, L., Dunsmore, C., Demaistre, E., Beavis, J., Moore, G., Schroda, A., Bowyer, A., Praefcke, G., Rosen, S., Martineau, N., Binder, N., Sidelmann, J.   +47 more
core  

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

Advanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch, Maximilian Holland, Klaus Drechsler, Johannes Schilp   +3 more
wiley   +1 more source

Evaluation of One-Stage Assays for the Monitoring of Recombinant Human Factor IX Padua Activity After Etranacogene Dezaparvovec Gene Therapy. [PDF]

Haemophilia
Astermark J, Miesbach W, Coppens M, Gielen S, Twisk J, Dolmetsch R, Verweij S, Monahan PE, Ewenstein BM, Nuthalapati S, Galante N, Young G, HOPE‐B study investigators.   +12 more
europepmc   +1 more source

Inverse Identification of Energy‐Dependent Laser Absorptivity in NiTi Laser Powder‐Bed Fusion via Calibrated Melt Pool Simulation

Advanced Engineering Materials, EarlyView.
A combined experimental–computational framework identifies energy‐dependent laser absorptivity for NiTi in laser powder‐bed fusion, applicable to conduction and transition modes. Single‐track experiments and thermofluid smoothed particle hydrodynamics simulations are coupled through inverse analysis of melt pool geometry.
Mohamadreza Afrasiabi, Hadi Moutablaleh, Ignatius A. Setiawan, Mehrshad Mehrpouya   +3 more
wiley   +1 more source

"An integrated multitool analysis contributes elements to interpreting unclassified factor IX missense variants associated with hemophilia B": comment from Lee et al. [PDF]

J Thromb Haemost
Lee K, DeSandre A, Samelson-Jones BJ.
europepmc   +1 more source

New AI‐Assisted Approach for Expanding the Solution Space: Application to Lattice Structure Design

Advanced Engineering Materials, EarlyView.
This work introduces an innovative framework for designing structured materials by ex panding the design space through reparameterization of qualitative variables into continuous structural descriptors. Combined with machine‐learning‐based prediction and multi‐objective optimization, the approach enables the discovery of novel lattice architectures ...
G. H. Gahimbare, Y. Beideler, D. Chune, R. De Guio, T. Roland, H. Chibane   +5 more
wiley   +1 more source

Cost-Effectiveness of Recombinant Factor IX Fc Prophylaxis and Recombinant Factor IX On-Demand Treatment in Patients with Haemophilia B Without Inhibitors. [PDF]

Adv Ther
Pochopien M, Tytuła A, Toumi M, Falk A, Martone N, Hakimi Z, Eriksson D.   +6 more
europepmc   +1 more source