Results 181 to 190 of about 123,267 (281)

Structural and functional insights into γ-glutamyl carboxylase-factor IX interaction: implications for vitamin K-dependent bleeding disorders. [PDF]

Haematologica
Liu K, Li S, Shen G, Tong J, Jiang N, Hong M, Gu Y, Chen L, Zhao Y, Huang J, Tie JK, Hao Z.   +11 more
europepmc   +1 more source

Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai, Jessica Fitzpatrick, Jing Li, Eric Roberts, Patricia Katz, Laura Plantinga, Gabriela Schmajuk, Jinoos Yazdany   +7 more
wiley   +1 more source

Population Modeling of Factor IX Activity Following Administration of Fidanacogene Elaparvovec Gene Therapy in Participants with Hemophilia B. [PDF]

Clin Pharmacokinet
Wojciechowski J, Gaitonde P, Hughes JH, Ravva P.   +3 more
europepmc   +1 more source

Factor VIII and Factor IX Activity Measurements for Hemophilia Diagnosis and Related Treatments. [PDF]

Semin Thromb Hemost, 2023
Bowyer AE, Gosselin RC.
europepmc   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

Arthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart, Anne Horne, Angelo Gaffo, Lisa K. Stamp, N. Lawrence Edwards, Nicola Dalbeth   +5 more
wiley   +1 more source

A precision gene-engineered B cell medicine producing sustained levels of active factor IX for hemophilia B therapy. [PDF]

Mol Ther
Liu H, Singh S, Mullen TJ, Bullock C, Keegan S, Patterson T, Thakur S, Lundberg A, Shenker S, Couto R, Yadav C, Dastagir S, Li L, Bainter W, Liberzon E, Malloy CR, Lazzarotto CR, Ohsumi TK, Chilakala S, Chen HM, Kshirsagar R, Hohmann AF, Arlauckas SP, Lazorchak A, Scull C, Morgan RA.   +25 more
europepmc   +1 more source

Differences in wild-type- and R338L-tenase complex formation are at the root of R338L-factor IX assay discrepancies. [PDF]

Blood Adv, 2023
Foley JH, Shehu E, Riddell A, Gray E, Goodale A, Yu IM, Verhoef D, Little J, Shattock D, Kitchen S, Chowdary P, Corbau R, Nathwani AC.   +12 more
europepmc   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

Evaluation of One-Stage Assays for the Monitoring of Recombinant Human Factor IX Padua Activity After Etranacogene Dezaparvovec Gene Therapy. [PDF]

Haemophilia
Astermark J, Miesbach W, Coppens M, Gielen S, Twisk J, Dolmetsch R, Verweij S, Monahan PE, Ewenstein BM, Nuthalapati S, Galante N, Young G, HOPE‐B study investigators.   +12 more
europepmc   +1 more source

Prediction of Surface Topography Parameters in Direct Laser Interference Patterning of Stainless Steel Using Infrared Monitoring and Convolutional Neural Networks

Advanced Engineering Materials, EarlyView.
This study presents an infrared monitoring approach for direct laser interference patterning (DLIP) combined with a convolutional neural network (CNN). Thermal emission data captured during structuring are used to predict surface topography parameters.
Lukas Olawsky, Marcelo Sallese, Leander Kläber, Clemens Kuhn, Keming Du, Andrés Fabián Lasagni   +5 more
wiley   +1 more source