Results 91 to 100 of about 166,342,389 (252)

Advances in the Protective Effects and Mechanisms of β‐Aminoisobutyric Acid in Maintaining Multi‐Organ Homeostasis

Medicine Bulletin, EarlyView.
ABSTRACT β‐Aminoisobutyric acid (BAIBA) is an exercise‐responsive myokine/metabolite released by skeletal muscle and has attracted increasing interest as a potential exercise mimetic and therapeutic candidate in preclinical research. BAIBA acts locally in skeletal muscle and can also reach distal organs through the circulation, contributing to the ...
Hao‐Zhe Wang, Wen‐Bi He, Fei‐Peng Chen, Jiong‐Xing Huang, Lin Zhu, Xiao‐Guang Liu   +5 more
wiley   +1 more source

Low-Cost Pedestrian Safety Zones: An Eight-Step Handbook [PDF]

Contract DTNH2216D00017/TaskOrder 693JJ919F000174This project consists of two reports, this one and Low-Cost Pedestrian Safety Zones: Countermeasure Selection Resource. They were developed for State Highway Safety Offices and transportation professionals
University of North Carolina at Chapel Hill. Highway Safety Research Center, Dunlap and Associates, Inc., Center for Education and Research in Safety   +2 more
core  

Optimal Transmission Performance of Quadrature Wireless Resonators at 3 T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To demonstrate a method for optimizing the efficiency of wireless resonators using tailored excitation from a dual‐transmit birdcage coil (BC), and to present the design and experimental investigation of a quadrature resonator for 3 T breast MRI application.
Leila Sharipova, Dmitrii Tikhonenko, Christophe Vilmen, David Bendahan, Stefan Enoch, Redha Abdeddaim, Alena Shchelokova, Marc Dubois   +7 more
wiley   +1 more source

Low-Cost Pedestrian Safety Zones: Countermeasure Selection Resource [PDF]

Contract DTNH2216D00017/TaskOrder 693JJ919F000174This project consists of two reports, this one and Low-Cost Pedestrian Safety Zones: Countermeasure Selection Resource. They were developed for State Highway Safety Offices and transportation professionals
University of North Carolina at Chapel Hill. Highway Safety Research Center, Dunlap and Associates, Inc., Center for Education and Research in Safety   +2 more
core  

Response to Ng et al. on “Stimulus‐induced arousal with transient electroencephalographic improvement distinguishes nonictal from ictal generalized periodic discharges”

Epilepsia, EarlyView.
Philippe Gélisse, William O. Tatum, Arielle Crespel, Peter W. Kaplan   +3 more
wiley   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.
ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada, Mary P. Choules, Frances A. Brightman, Shigeru Takeshita, Shinsuke Nakao, Nobuaki Amino, Takeshi Nakayama, Masato Takeuchi, Kanji Komatsu, Fernando Ortega, Hitesh Mistry, David Orrell, Christophe Chassagnole, Peter L. Bonate   +13 more
wiley   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source

Influence of Sampling Methods on the Accuracy of Machine Learning Predictions Used for Strain-Dependent Slope Stability

Geosciences
Supervised machine learning (ML) techniques have been widely used in various geotechnical applications. While much attention is given to the ML techniques and the specific geotechnical problem being addressed, the influence of sampling methods on ML ...
Sudan Shakya, Christoph Schmüdderich, Jan Machaček, Luis Felipe Prada-Sarmiento, Torsten Wichtmann   +4 more
doaj   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source