Results 171 to 180 of about 166,342,389 (252)

Bioactive Compounds and Cytotoxicity of Seed and Leaf Oils of Moringa oleifera

open access: yeseFood, Volume 7, Issue 5, October 2026.
Among the practical applications of the oils described in this study, their use as an ingredient in food stands out, as well as the potential for developing bioactive materials for packaging, conferring antioxidant and antimicrobial properties. Seed and leaf oils from Moringa oleifera exhibit functional properties of industrial interest and bioactive ...
Emanuela de Lima Viana   +12 more
wiley   +1 more source

An Inferential‐Based Model of Scrupulosity and Obsessive–Compulsive Disorder Across Cultures: The Roles of Fear of Self and Obsessive Beliefs

open access: yesJournal of Clinical Psychology, Volume 82, Issue 10, Page 1661-1672, October 2026.
ABSTRACT Although inferential confusion (IC), fear of self (FOS), and obsessive beliefs have each been linked to obsessive–compulsive disorder (OCD), they have rarely been examined together within the inferential‐based approach (IBA) or considered across different cultural contexts. This study examined a cross‐sectional model in which IC was associated
Mujgan Inozu   +8 more
wiley   +1 more source

Adaptive multihazard modeling predicts rainfall-driven dam failure: a case study. [PDF]

open access: yesSci Rep
Nasser M   +4 more
europepmc   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

Best practices for cryo‐trapping time‐resolved crystallography with the Spitrobot crystal plunger

open access: yesProtein Science, Volume 35, Issue 10, October 2026.
Abstract Capturing meta‐stable conformations of enzymes and ligand complexes demands structural snapshots beyond static crystal structures. While time‐resolved serial crystallography at room temperature offers a time‐resolution down to the femto‐second domain, it requires large amounts of micro crystals, specialized beamlines, and considerable ...
Robert Bosman   +7 more
wiley   +1 more source

Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 19, Page 5701-5731, October 2026.
Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley   +1 more source

Oligosaccharide prebiotics in functional foods and therapeutics: innovations and challenges. [PDF]

open access: yes3 Biotech
Sandra KS   +6 more
europepmc   +1 more source

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