Results 101 to 110 of about 2,368,168 (302)

$D \rightarrow K, l \nu$ Semileptonic Decay Scalar Form Factor and $|V_{cs}|$ from Lattice QCD

, 2010
We present a new study of D semileptonic decays on the lattice which employs the Highly Improved Staggered Quark (HISQ) action for both the charm and the light valence quarks.
Christine T. H. Davies, Eduardo Follana, G. Peter Lepage, H. Na, Heechang Na, J. Bailey, Junko Shigemitsu, S. Simula   +7 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

X-ray Observation of Mars with Suzaku at Solar Minimun

, 2011
Mars was observed in X-rays during April 3-5 2008 for 82 ksec with the Japanese Suzaku observatory. Mars has been known to emit X-rays via the scattering of solar X-rays and via the charge exchange between neutral atoms in the exosphere and solar wind ...
Ezoe, Yuichiro, Futaana, Yoshifumi, Ishikawa, Kumi, Ohashi, Takaya, Terada, Naoki   +4 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Allium hirtifolium Boiss: Radical scavenging property and the lowering effects on blood fibrinogen and factor VII [PDF]

, 2012
Enhancement of blood fibrinogen or factor VII increases cardiovascular diseases. Allium hirtifolium Boiss (Mosir) has been shown to have cardioprotective effect.
Ansari Samani, Roya., Asgari, Sedigheh., Deris, Fatemeh., Hojjati, Mohammad reza., Pourgheysari, Batoul., Rafieian-Kopaei, Mahmoud., Salimi, Mahmoud., Shahinfard, Najmeh.   +7 more
core  

Equation of State of H2O Ice Using Melt-Recrystallization

, 2019
The recent surge in exoplanet discoveries due to advancements in astrophysical technology and analysis has brought the reliability of early equation of state measurements into question as they are the limiting factor when modeling composition of these ...
Grande, Zachary Michael
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Estudio familiar de las hemofilias A y B: 5 años de experiencia en la detección de portadoras Family study of hemophilia A and B: 5 years of experience in carrier detection

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2010
La hemofilia se caracteriza por ser una enfermedad congénita del trastorno de la coagulación y constituye un desorden recesivo ligado al cromosoma X. El estudio molecular se realiza por estudios indirectos por ser causada por mutaciones heterogéneas en ...
Yaixa Piloto Roque, Teresa Collazo Mesa, Manuel Gómez Martínez, Yadira Hernández Pérez, Yulemi Gónzalez Quesada, Ilienis Giraldo Rico, Lídice Reyes Navarro   +6 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source