Results 11 to 20 of about 163,074 (266)
Seminars in Thrombosis and Hemostasis, 2009 The complex formed between the procoagulant serine protease activated factor VII (FVII) and the membrane protein tissue factor, exposed on the vascular lumen upon injury, triggers the initiation of blood clotting. This review describes the clinical picture of FVII deficiency and provides information on diagnosis and management of the disease.
G. Mariani, BERNARDI, Francesco
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Inhibitors to factor
Haemophilia, 2014 We performed a prospective study of FVII inhibitor occurrence in a large number of patients with FVII deficiency who had received replacement therapy for spontaneous or traumatic bleeding episodes, major or minor surgical interventions or prophylaxis.Inhibitor development was detected in 2.6% (3/115) of patients, but the incidence of de novo inhibitors
Batorova A +11 more
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Blood Coagulation & Fibrinolysis, 2002 As yet, there have been neither systematic reviews nor reports of randomized, controlled trials involving factor VII (FVII) deficiency. Hence, a picture of this disorder can only be drawn by reviewing and summarizing the data that is available. This article provides an overview of the understanding of this rare, inherited disorder of coagulation.
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Pharmacokinetics of Factor VII
Blood, 2011 Abstract Abstract 2259 Introduction: In Congenital Bleeding Disorders (CBD), efficacy of Replacement Therapy (RT) can be indirectly measured on the basis of pharmacokinetic (PK) methods.
Morfini,M +7 more
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Haematologica, 2015 Standard treatment for Glanzmann thrombasthenia is platelet transfusion. Recombinant activated factor VII has been shown to be successful in patients with Glanzmann thrombasthenia with platelet antibodies or who are refractory to platelet transfusions ...
Giovanni Di Minno +5 more
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Çocuk Dergisi, 2023 Objective: Patients with a rare factor deficiency (RFD) may be asymptomatic or present with life-threatening bleeding. Studies have shown no direct relationship between factor activity level and bleeding severity, with difficulties being experienced in ...
Işık Odaman Al +3 more
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Acute Myelogenous Leukemia With Trisomy 8 and Concomitant Acquired Factor VII Deficiency
Journal of Investigative Medicine High Impact Case Reports, 2019 Acquired isolated factor VII deficiency is a rare bleeding disorder and has been reported in 31 cases. This is in contrast to congenital factor VII deficiency, which while also infrequent is the most common rare congenital bleeding disorder.
Leila Moosavi MD +4 more
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Scientific Reports, 2021 Altered coagulation has been reported in people living with HIV (PLWH) with ongoing viral replication and may predispose to cardiovascular diseases. However, less is known about coagulation in PLWH with undetectable viral replication.
Asbjørn Fink +9 more
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Factor VII verona coagulation disorder: double heterozygosis with an abnormal factor VII and heterozygous factor VII deficiency [PDF]
Blood, 1977 A family with a peculiar defect of factor VII is described. The propositi, a brother and sister, were born of a nonconsanguineous marriage and presented a mild to moderate bleeding tendency since childhood (epistaxis, excessive bleeding after tooth extraction).
A, Girolami +4 more
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Safe Neuraxial Anesthesia in a Pregnant Patient with Congenital Factor VII Deficiency: A Case Report
Journal of Obstetric Anaesthesia and Critical CareCongenital factor VII deficiency is a rare autosomal recessive bleeding disorder with a variable clinical phenotype, ranging from asymptomatic individuals to those with severe hemorrhage.
Keith Asselborn +3 more
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