Results 11 to 20 of about 154,396 (266)

Case Report: Factor VII Deficiency Presented With Cephalohematoma After Birth

Frontiers in Pediatrics, 2021
Introduction: Factor VII deficiency is a rare inherited autosomal recessive bleeding disorder with a global prevalence of 1/500,000. Most cases remain asymptomatic, and cases with severe clinical presentation are rarely reported.Case Presentation: A ...
Yuan-Chun Lo, Ching-Tien Peng, Ching-Tien Peng, Yin-Ting Chen   +3 more
doaj   +1 more source

Pharmacokinetics of Factor VII

Blood, 2011
Abstract Abstract 2259 Introduction: In Congenital Bleeding Disorders (CBD), efficacy of Replacement Therapy (RT) can be indirectly measured on the basis of pharmacokinetic (PK) methods.
Morfini,M, Martinovitz, U, Batorova, A, Dolce,A, NAPOLITANO, Mariasanta, Ingerslev,J, Schved,JF, Mariani,G   +7 more
openaire   +2 more sources

Asymptomatic intracranial hemorrhage in a newborn with congenital factor VII deficiency and successful treatment with recombinant activated factor VII

The Turkish Journal of Pediatrics, 2018
Intracranial hemorrhage is considered the most common cause of death in newborns with congenital factor VII (FVII) deficiency. Recombinant activated FVII (rFVIIa) provides specific replacement therapy, however there is limited experience with its ...
Zeynep İnce, Özgül Bulut, Melike Tuğrul-Aksakal, Ayşegül Ünüvar, Ömer Devecioğlu, Asuman Çoban   +5 more
doaj   +1 more source

Prophylaxis in congenital factor VII deficiency: indications, efficacy and safety. Results from the Seven Treatment Evaluation Registry (STER)

Haematologica, 2013
Because of the very short half-life of factor VII, prophylaxis in factor VII deficiency is considered a difficult endeavor. The clinical efficacy and safety of prophylactic regimens, and indications for their use, were evaluated in factor VII-deficient ...
Mariasanta Napolitano, Muriel Giansily-Blaizot, Alberto Dolce, Jean F. Schved, Guenter Auerswald, Jørgen Ingerslev, Jens Bjerre, Carmen Altisent, Pimlak Charoenkwan, Lisa Michaels, Ampaiwan Chuansumrit, Giovanni Di Minno, Ümran Caliskan, Guglielmo Mariani   +13 more
doaj   +1 more source

Factor VII verona coagulation disorder: double heterozygosis with an abnormal factor VII and heterozygous factor VII deficiency [PDF]

Blood, 1977
A family with a peculiar defect of factor VII is described. The propositi, a brother and sister, were born of a nonconsanguineous marriage and presented a mild to moderate bleeding tendency since childhood (epistaxis, excessive bleeding after tooth extraction).
A, Girolami, G, Falezza, G, Patrassi, M, Stenico, L, Vettore   +4 more
openaire   +3 more sources

The international, prospective Glanzmann Thrombasthenia Registry: treatment modalities and outcomes of non-surgical bleeding episodes in patients with Glanzmann thrombasthenia

Haematologica, 2015
Standard treatment for Glanzmann thrombasthenia is platelet transfusion. Recombinant activated factor VII has been shown to be successful in patients with Glanzmann thrombasthenia with platelet antibodies or who are refractory to platelet transfusions ...
Giovanni Di Minno, Rainer B Zotz, Roseline d’Oiron, Niels Bindslev, Matteo Nicola Dario Di Minno, Man-Chiu Poon   +5 more
doaj   +1 more source

Evaluation of Clinical Features, Laboratory Findings and Treatment of Patients with Rare Factor Deficiency: A Retrospective Single Center Experience

Çocuk Dergisi, 2023
Objective: Patients with a rare factor deficiency (RFD) may be asymptomatic or present with life-threatening bleeding. Studies have shown no direct relationship between factor activity level and bleeding severity, with difficulties being experienced in ...
Işık Odaman Al, Tuba Hilkay Karapınar, Salih Gözmen, Yeşim Oymak   +3 more
doaj   +1 more source

Identification of two different coagulation phenotypes in people living with HIV with undetectable viral replication

Scientific Reports, 2021
Altered coagulation has been reported in people living with HIV (PLWH) with ongoing viral replication and may predispose to cardiovascular diseases. However, less is known about coagulation in PLWH with undetectable viral replication.
Asbjørn Fink, Andreas Dehlbæk Knudsen, Rebekka Faber Thudium, Jakob Hjorth Von Stemann, Shoaib Afzal, Jens Lundgren, Ditte Marie Kirkegaard-Klitbo, Sisse Rye Ostrowski, Børge G. Nordestgaard, Susanne Dam Nielsen   +9 more
doaj   +1 more source

Acute Myelogenous Leukemia With Trisomy 8 and Concomitant Acquired Factor VII Deficiency

Journal of Investigative Medicine High Impact Case Reports, 2019
Acquired isolated factor VII deficiency is a rare bleeding disorder and has been reported in 31 cases. This is in contrast to congenital factor VII deficiency, which while also infrequent is the most common rare congenital bleeding disorder.
Leila Moosavi MD, Jonathan Bowen BSc, Jeffrey Coleman MD, Arash Heidari MD, Everardo Cobos MD   +4 more
doaj   +1 more source

Case of concurrent factor VII and factor XI deficiencies manifesting as spontaneous lower extremity compartment syndrome

Clinical Case Reports, 2022
Factor VII and XI deficiencies are rare bleeding disorders typically associated with mild or provoked bleeding. This case report describes a patient with factor VII and XI deficiencies with an unprovoked episode of lower extremity hematoma causing ...
Joseph P. Marshalek, David Yashar, Karen Huynh, Sarah Tomassetti   +3 more
doaj   +1 more source