The Many Faces of Protease-Activated Receptor 2 in Kidney Injury
BiomedicinesProtease-activated receptor 2 (PAR2) is a seven-transmembrane, G-protein-coupled receptor that is activated by coagulation proteases such as factor VIIa and factor Xa and other serine proteases.
Yuji Oe +2 more
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How the tissue factor-VIIa complex keeps two substrates in the loop. [PDF]
J Thromb Haemost, 2021 Schulman S.
europepmc +1 more source
Bronchoscopic Intrapulmonary Recombinant Factor VIIa for Diffuse Alveolar Hemorrhage-induced Acute Respiratory Failure in MPO-ANCA Vasculitis: A Case Report. [PDF]
J Crit Care Med (Targu Mures), 2022 Smesseim I +8 more
europepmc +1 more source
The Turkish Journal of Pediatrics, 2003 Transfusion of platelet concentrates remains the first-line therapy for Glanzmann thrombasthenia in case of bleeding or preparation for surgery. However, development of antibodies to platelet glycoprotein (Gp) IIb/IIIa complex or human leukocyte ...
Omer Devecioğlu +5 more
doaj
Intergenerational mobility of socio-economic status in comparative perspective [PDF]
This paper reviews three strands of literature on socio-economic intergenerational mobility. The first is a mostly recent and rapidly growing economics literature that measures mobility in labour earnings and income.
Anders Björklund, Markus Jäntti
core
Factor VIIa Regulates the Level of Cell-Surface Tissue Factor through Separate but Cooperative Mechanisms. [PDF]
Cancers (Basel), 2021 Madkhali Y +5 more
europepmc +1 more source
Economic Boom and Social Mobility: The Irish Experience [PDF]
In this paper we examine the consequences for social mobility patterns of the unprecedented period of economic growth experienced in Ireland over the 1990s and the implications of developments for current theories of social fluidity.
Christopher T. Whelan, Richard Layte
core
A serine loop in tissue factor mediates substrate selectivity by the tissue factor-factor VIIa complex. [PDF]
J Thromb Haemost, 2021 Birkle F, Morrissey JH.
europepmc +1 more source
A systematic approach for evaluating the role of surface-exposed loops in trypsin-like serine proteases applied to the 170 loop in coagulation factor VIIa. [PDF]
Sci Rep, 2022 Sorensen AB +10 more
europepmc +1 more source