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SUPPRESSION OF FACTOR VIII ANTIBODY BY COMBINED FACTOR VIII AND CYCLOPHOSPHAMIDE
Acta Medica Scandinavica, 1974Abstract. Four patients with severe haemophilia A complicated by inhibitors of factor VIII (corresponding to 0.5, 0.7, 1.0 and 2.5 U/ml plasma) and a non‐haemophilic woman with an acquired inhibitor of factor VIII (corresponding to 160 U/ml plasma) have been treated with a large single dose of factor VIII concentrate (4 000–8 000 U factor VIII) and ...
I M, Nilsson, U, Hedner, L, Holmberg
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Porcine factor VIII therapy in patients with factor VIII inhibitors
1995A review is presented of the use of porcine factor VIII (F.VIII) in patients with F.VIII inhibitors and acquired or congenital hemophilia. This review is drawn partly from the published literature and partly from an international survey of the use of porcine F.VIII in patients with congenital hemophilia conducted under the auspices of the ISTH F.VIII ...
C, Hay, J N, Lozier
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Porcine Factor VIII in Factor VIII Antibody-Positive Hemophiliacs
Journal of Interferon Research, 1994rected against the factor VIII protein, and completely or partially neutralizing the plasma coagulant activity of the clotting factor, is associated with a variety of diseases, and these antibodies are often the cause of the life-threatening bleeds. Such inhibitors, designated as acquired hemophilia, are uncommon (found in 0.2-1.0 previously normal ...
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The Absorption of Human Factor VIII Neutralizing Antibody by Factor VIII
British Journal of Haematology, 1974Summary. A new technique has been devised for measuring the amount of human factor VIII neutralizing antibody that is absorbed by factor VIII. The method has been applied to factor VIII from normal donors and to factor VIII‐like antigen from haemophilic persons.
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