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A Rare Cause of Acquired Factor X Deficiency in an 87-Year-Old Female [PDF]

open access: goldCase Reports in Hematology, 2021
Factor X deficiency is a rare coagulopathy that can be inherited or acquired. Acquired factor X deficiency has been associated with plasma cell dyscrasias, amyloids, and use of vitamin K antagonists.
Ayrton Bangolo   +6 more
doaj   +3 more sources

Inherited Moderate Factor X Deficiency Presenting as Cardiac Tamponade [PDF]

open access: goldCase Reports in Hematology, 2019
Factor X deficiency is a rare bleeding disorder that varies in the severity of its clinical manifestations. The symptoms of this disorder can occur at any age, although most severe cases appear in childhood.
Tamer Othman   +4 more
doaj   +3 more sources

Plasma‐derived factor X concentrate compassionate use for hereditary factor X deficiency: Long‐term safety and efficacy in a retrospective data‐collection study

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2021
Background Coagadex is a high‐purity plasma‐derived factor X concentrate (pdFX) developed to treat hereditary factor X deficiency (FXD). Objective Evaluate the efficacy and safety of pdFX administered to patients with hereditary FXD.
James N. Huang   +4 more
doaj   +2 more sources

Acquired factor X deficiency in patients with amyloid light-chain amyloidosis: incidence, bleeding manifestations, and response to high-dose chemotherapy [PDF]

open access: bronzeBlood, 2001
Acquired deficiency of factor X occurs in patients with systemic amyloid light-chain (AL) amyloidosis, presumably due to adsorption of factor X to amyloid fibrils.
Élie Choufani   +6 more
openalex   +2 more sources

Acquired Factor X Deficiency in Patients With Primary Light Chain Amyloidosis

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2019
Acquired factor X (FX) deficiency is a rare but serious complication of primary amyloidosis, presumably caused by the binding of amyloid proteins to the clotting factors.
Siroj Dejhansathit MD   +1 more
doaj   +2 more sources

Use of plasma‐derived factor X concentrate in neonates and infants with congenital factor X deficiency [PDF]

open access: bronzeJournal of Thrombosis and Haemostasis, 2020
Congenital factor X deficiency (FXD) is a rare bleeding disorder that often presents with severe bleeding in the neonatal period. Long‐term prophylaxis with infusions of FX‐containing products is recommended in patients with FXD and a personal or family ...
Karen L. Zimowski   +5 more
openalex   +2 more sources

Occurrence and management of severe bleeding episodes in patients with hereditary factor X deficiency

open access: greenHaemophilia, 2021
Vitamin K–dependent factor X (FX) plays an important role in thrombin formation, and a deficiency in FX can cause impaired coagulation, the severity of which is usually correlated with the degree of deficiency.
Michael D. Tarantino
openalex   +3 more sources

Neonatal presentation of factor X deficiency

open access: diamondIndian Journal of Health Sciences and Biomedical Research KLEU
Factor X is a Vitamin K-dependent serine protease synthesized in the liver. It is a key factor of the coagulation cascade as it is the first enzyme of a common pathway that leads to the formation of a stable fibrin clot.
Arjani Patra   +3 more
doaj   +2 more sources

Factor XI deficiency in Indian Bos taurus, Bos indicus, Bos taurus x Bos indicus crossbreds and Bubalus bubalis [PDF]

open access: goldGenetics and Molecular Biology, 2007
We investigated the occurrence of Factor XI (FXI) deficiency syndrome in the following Indian dairy animals: Bos taurus Holstein-Friesian and Jersey cattle, Bos indicus Indian cattle breeds, B. taurus x B. indicus crossbreds and the river buffalo Bubalus
Rajesh K. Patel   +4 more
doaj   +2 more sources

Factor XDebrecen: Gly204Arg mutation in factor X causes the synthesis of a non-secretable protein and severe factor X deficiency

open access: goldHaematologica, 2008
Due to a homozygous Gly204Arg mutation in the factor X (FX) gene no detectable FX antigen was found in the plasma of a one-year old patient with severe bleeding diathesis.
Zsuzsanna Bereczky   +7 more
doaj   +3 more sources

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