Results 101 to 110 of about 989,774 (270)

Partial gene deletion in a family with factor X deficiency [PDF]

, 1989
Fabı́ola Del Carlo Bernardi, Giovanna Marchetti, P. Patracchini, Stefano Volinia, Donato Gemmati, Paolo Simioni, A Girolami   +6 more
openalex   +3 more sources

Bone matrix components activate the NLRP3 inflammasome and promote osteoclast differentiation [PDF]

, 2017
The NLRP3 inflammasome senses a variety of signals referred to as danger associated molecular patterns (DAMPs), including those triggered by crystalline particulates or degradation products of extracellular matrix. Since some DAMPs confer tissue-specific
Abu-Amer, Yousef, Alippe, Yael, Civitelli, Roberto, Mbalaviele, Gabriel, Novack, Deborah V, Qu, Chao, Ricci, Biancamaria, Wang, Chun, Xiao, Jianqiu, Zou, Wei   +9 more
core   +2 more sources

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source

Molecular hydrogen deficiency in HI-poor galaxies and its implications for star formation

, 2009
We use a sample of 47 homogeneous and high sensitivity CO images taken from the Nobeyama and BIMA surveys to demonstrate that, contrary to common belief, a significant number (~40%) of HI-deficient nearby spiral galaxies are also depleted in molecular ...
Alessandro Boselli, Bigiel, Boselli, Boselli, Boselli, Boselli, Casoli, Faber, Gallazzi, Giovanelli, Giuseppe Gavazzi, Helfer, J. Xavier Prochaska, James, Kennicutt, Kennicutt, Kennicutt, Koopmann, Krumholz, Krumholz, Kuno, Mark R. Krumholz, Michele Fumagalli, Prochaska, Rengarajan, Springob, Tully, Walter, Wilson, Wong   +29 more
core   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Iron economy in Chlamydomonas reinhardtii. [PDF]

, 2013
While research on iron nutrition in plants has largely focused on iron-uptake pathways, photosynthetic microbes such as the unicellular green alga Chlamydomonas reinhardtii provide excellent experimental systems for understanding iron metabolism at the ...
Blaby-Haas, Crysten E, Glaesener, Anne G, Merchant, Sabeeha S   +2 more
core   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

FEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman, Annika Egeler, Saskia Rödl, Johannes M. Herrmann   +3 more
wiley   +1 more source

Molecular gas in late-type galaxies

, 2001
We present $^{12}$CO(J=1--0) line observations of 22 low-luminosity spiral galaxies in the Virgo cluster. These data, together with 244 others available in the literature, allow us to build a large sample that we use to study the molecular gas properties
A. Boselli, Allen, Allen, Alton, Alton, Arimoto, Bianchi, Bicay, Binggeli, Binggeli, Boissier, Bolatto, Boselli, Boselli, Boselli, Boselli, Boselli, Boselli, Boselli, Bouchet, Casoli, Casoli, Cayatte, Contursi, Devereux, Devereux, Devereux, G. Gavazzi, Gavazzi, Gavazzi, Gavazzi, Gavazzi, Gavazzi, Gavazzi, Gavazzi, Gavazzi, Guélin, Guélin, Haynes, Haynes, Helou, Hoffman, Hoffman, Hoffman, Hoopes, Hunter, Hunter, Israel, J. Lequeux, Kaufman, Kenney, Kenney, Kenney, Kennicutt, Kennicutt, Kennicutt, Kennicutt, Kennicutt, Kennicutt, Kennicutt, Kobulnicky, Koornneef, Lequeux, Magri, Moss, Neininger, Polk, Rand, Rubio, Rubio, Sage, Schmidt, Schneider, Scodeggio, Sodroski, Strong, Taylor, Taylor, Thuan, van den Bergh, Walterbos, Wild, Wilson, Young, Young, Young, Zaritsky   +86 more
core   +2 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source