Rank-deficiencies in a reduced information latent variable model [PDF]
Latent variable models are well-known to suffer from rank deficiencies, causing problems with convergence and stability. Such problems are compounded in the "reduced-group split-ballot multitrait-multimethod model", which omits a set of moments from the estimation through a planned missing data design.
arxiv
Congenital Factor X-Riyadh (Stuart-Prower) Deficiency With Isolated Prothrombin Time Prolongation: A Case Report [PDF]
Badriah G Alasmari+5 more
openalex +1 more source
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien+7 more
wiley +1 more source
A note on the probability of a groupoid having deficient sets [PDF]
A subset $X$ of a groupoid is said to be deficient if $|X \cdot X|\leq |X|$. It is well-known that the probability that a random groupoid has a deficient $t$-element set with $t\geq 3$ is zero. However, as conjectured in [4], we show that the probability is not zero in the case of sets of two elements and calculate the exact value.
arxiv
Acquired factor X deficiency in patients with amyloid light-chain amyloidosis: incidence, bleeding manifestations, and response to high-dose chemotherapy [PDF]
Élie Choufani+6 more
openalex +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Gene mutations and three‐dimensional structural analysis in 13 families with severe factor X deficiency [PDF]
Flora Peyvandi+7 more
openalex +1 more source
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh+6 more
wiley +1 more source
A review of the pharmacokinetics, efficacy and safety of high-purity factor X for the prophylactic treatment of hereditary factor X deficiency. [PDF]
Payne J+4 more
europepmc +1 more source
Intracerebral Haemorrhage in an Adult due to Transient Factor X Deficiency [PDF]
Timothy Young+4 more
openalex +1 more source