Results 121 to 130 of about 1,112,515 (342)

On the small prime factors of a non-deficient number [PDF]

arXiv, 2020
Let $\sigma(n)$ to be the sum of the positive divisors of $n$. A number is non-deficient if $\sigma(n) \geq 2n$. We establish new lower bounds for the number of distinct prime factors of an odd non-deficient number in terms of its second smallest, third smallest and fourth smallest prime factors.
arxiv  

The farnesoid X receptor negatively regulates osteoclastogenesis in bone remodeling and pathological bone loss

, 2017
Farnesoid X receptor (FXR, NR1H4) is a member of the nuclear receptor superfamily of ligand-activated transcription factors. Since the role of FXR in osteoclast differentiation remains ill-defined, we investigated the biological function of FXR on ...
Kang, Ju-Hee, Kim, Jung-Woo, Koh, Jeong-Tae, Lim, Hyungsik, Shin, Chan Soo, Sim, Jung-Sun, Yim, Mijung, Zheng, Ting   +7 more
core   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

CHARACTERIZATION AND MANAGEMENT OF PATIENTS WITH HEREDITARY FACTOR X DEFICIENCY: A RETROSPECTIVE SINGLE CENTER EXPERIENCE

Hematology, Transfusion and Cell Therapy, 2023
Objective: Factor X deficiency (FXd) is a rare coagulation disorder that can be either hereditary or acquired. Case report: We characterized patients with FXd and evaluated their bleeding patterns and treatment strategies. Methodology: This retrospective
Nigar Abdullayeva, Fahri Sahin, Zuhal Demirci, Bahar Sevgili   +3 more
doaj  

Differential phenotypic expression of a novel PDHA1 mutation in a female monozygotic twin pair [PDF]

, 2019
Pyruvate dehydrogenase complex (PDC) deficiency caused by mutations in the X-linked PDHA1 gene has a broad clinical presentation, and the pattern of X-chromosome inactivation has been proposed as a major factor contributing to its variable expressivity ...
Brooks, T, Brown, GK, Brown, RM, Bugiardini, E, Gago, F, Hanna, MG, Hargreaves, IP, Horga, A, Houlden, H, Manole, A, Mills, A, Pareés, I, Parton, MJ, Pitceathly, RDS, Polke, JM, Rahman, S, Reilly, MM, Remzova, E, Sweeney, MG, Woodward, CE   +19 more
core  

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Spectral Factorization of Rank-Deficient Polynomial Matrix-Functions [PDF]

arXiv, 2010
A spectral factorization theorem is proved for polynomial rank-deficient matrix-functions. The theorem is used to construct paraunitary matrix-functions with first rows given.
arxiv  

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Acquired Vitamin K Deficiency as Unusual Cause of Bleeding Tendency in Adults: A Case Report of a Nonhospitalized Student Presenting with Severe Menorrhagia

Case Reports in Obstetrics and Gynecology, 2017
We report a rare case of acquired vitamin K deficiency presenting with severe menorrhagia and without any gynecological problem. Partial thromboplastin time (59.2 seconds) and prothrombin time (33.1 seconds, INR: 5.97) were considerably prolonged in ...
Omid Reza Zekavat, Gholamreza Fathpour, Sezaneh Haghpanah, Seyed Javad Dehghani, Maryam Zekavat, Nader Shakibazad   +5 more
doaj   +1 more source

The HI content of the Eridanus group of galaxies [PDF]

, 2005
The HI content of galaxies in the Eridanus group is studied using the GMRT observations and the HIPASS data. A significant HI deficiency up to a factor of 2-3 is observed in galaxies in the high galaxy density regions. The HI deficiency in galaxies is observed to be directly correlated with the local projected galaxy density, and inversely correlated ...
arxiv   +1 more source