Results 161 to 170 of about 1,112,515 (342)

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Application value of contrast‐enhanced ultrasound in preoperative localization of microwave ablation for primary hyperparathyroidism

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Background Ultrasonography (US) and 99mTechnetium‐sestamibi scintigraphy (99mTc‐MIBI) are currently first‐line imaging modalities to localize parathyroid adenomas with sensitivities of 80% and 84%, respectively. Therefore, finding other modalities to further improve the diagnostic accuracy for preoperative localization is critically needed ...
Fangyi Liu, Li Zang, Yunlin Li, Zhiwei Guan, Yang Liu, Xiaoling Yu, Zhiyu Han, Ping Liang   +7 more
wiley   +1 more source

A note on the probability of a groupoid having deficient sets [PDF]

arXiv
A subset $X$ of a groupoid is said to be deficient if $|X \cdot X|\leq |X|$. It is well-known that the probability that a random groupoid has a deficient $t$-element set with $t\geq 3$ is zero. However, as conjectured in [4], we show that the probability is not zero in the case of sets of two elements and calculate the exact value.
arxiv  

Acquired factor X deficiency in patients with amyloid light-chain amyloidosis: incidence, bleeding manifestations, and response to high-dose chemotherapy [PDF]

, 2001
Élie Choufani, Vaishali Sanchorawala, Timothy J. Ernst, Karen Quillen, Martha Skinner, Daniel G. Wright, David C. Seldin   +6 more
openalex   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

Evaluation of an EPID in vivo monitoring system using local and external independent audit measurements

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose The aim of this work was to evaluate the SunCHECK PerFRACTION, the software for in vivo monitoring using EPID images. Materials/Methods First, the PerFRACTION ability to detect errors was investigated simulating two situations: (1) variation of LINAC output and (2) variation of the phantom thickness.
Samuel Ramalho Avelino, Juliana Rosada Dias, Taís Marques Peron, Gabriel Souza Vidal   +3 more
wiley   +1 more source

Gene mutations and three‐dimensional structural analysis in 13 families with severe factor X deficiency [PDF]

, 2002
Flora Peyvandi, Marzia Menegatti, Elena Santagostino, Sepideh Akhavan, James Uprichard, David J. Perry, Stephen J. Perkins, Pier Mannuccio Mannucci   +7 more
openalex   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

A review of the pharmacokinetics, efficacy and safety of high-purity factor X for the prophylactic treatment of hereditary factor X deficiency. [PDF]

Haemophilia, 2022
Payne J, Batsuli G, Leavitt AD, Mathias M, McGuinn CE.   +4 more
europepmc   +1 more source

Intracerebral Haemorrhage in an Adult due to Transient Factor X Deficiency [PDF]

, 2003
Timothy Young, B P Chitnavis, Elyse Swallow, Roopen Arya, Bipin Vadher   +4 more
openalex   +1 more source