Results 11 to 20 of about 989,774 (270)

Factor X deficiency: An overlooked cause of bleeding in the newborn

Asian Journal of Transfusion Science, 2023
Inherited factor X (FX) deficiency is a rare autosomal recessive bleeding disorder, presenting with various bleeding manifestations ranging from nonspecific bruising to life-threatening intracranial hemorrhage.
Shalini Verma, Shalini Tripathi, Mala Kumar   +2 more
doaj   +2 more sources

Inherited Moderate Factor X Deficiency Presenting as Cardiac Tamponade [PDF]

Case Reports in Hematology, 2019
Factor X deficiency is a rare bleeding disorder that varies in the severity of its clinical manifestations. The symptoms of this disorder can occur at any age, although most severe cases appear in childhood.
Tamer Othman, Ayman Abdelkarim, Karen Huynh, An Uche, Jennifer Lee   +4 more
doaj   +2 more sources

SUCCESSFUL MANAGEMENT OF SEVERE CONGENITAL FACTOR X DEFICIENCY DURING PREGNANCY AND LABOR WITH PCC IN TWO SISTERS

Hematology, Transfusion and Cell Therapy, 2022
Introduction: Factor X (FX) deficiency is an autosomal recessive disorder caused by quantitative or qualitative defects in the FX protein. FX deficiency has an estimated worldwide prevalence of one in 1000000.
Alfadil Haroon, Riad Elfakih, Hazzaa Alzahrani   +2 more
doaj   +2 more sources

Combined Factor VII and X Deficiency [PDF]

Online Journal of Health & Allied Sciences, 2011
Factor VII deficiency and factor X deficiency and very rare disorders individually. Combined Factor VII and X is a rare congenital blood disorder with very few cases reported in the literature.
Gursharan Singh Narang,, Sunita Arora,, Jivtesh Singh Pahwa,   +2 more
doaj   +1 more source

A rare case of factor X deficiency induced by valproic acid [PDF]

Research and Practice in Thrombosis and Haemostasis
Background: Factor X (FX) deficiency (FXD) significantly disrupts coagulation, potentially leading to severe bleeding. While inherited FXD is rare, with a prevalence of 1 in 500,000, acquired FXD is also uncommon and frequently linked to conditions such ...
Pierre-Antonin Rigon, Vincent Ernest
doaj   +2 more sources

Plasma‐derived factor X concentrate compassionate use for hereditary factor X deficiency: Long‐term safety and efficacy in a retrospective data‐collection study [PDF]

Research and Practice in Thrombosis and Haemostasis, 2021
Background Coagadex is a high‐purity plasma‐derived factor X concentrate (pdFX) developed to treat hereditary factor X deficiency (FXD). Objective Evaluate the efficacy and safety of pdFX administered to patients with hereditary FXD.
James N. Huang, Ri Liesner, Steven K. Austin, Kaan Kavakli, Chioma Akanezi   +4 more
doaj   +2 more sources

Severe Congenital Factor X Deficiency as a First Case Report in Cambodia [PDF]

Case Reports in Hematology
Conclusion: FX deficiency, though rare, should be considered in the differential diagnosis of pediatric patients presenting with recurrent gingival or mucocutaneous bleeding in conjunction with prolonged PT and APTT.
Chin Soey, Meang Sovandos, Lam Pechkethia, Lean Kimsreng, Chean Sophâl   +4 more
doaj   +2 more sources

Factor XDebrecen: Gly204Arg mutation in factor X causes the synthesis of a non-secretable protein and severe factor X deficiency

Haematologica, 2008
Due to a homozygous Gly204Arg mutation in the factor X (FX) gene no detectable FX antigen was found in the plasma of a one-year old patient with severe bleeding diathesis.
Zsuzsanna Bereczky, Helga Bárdos, István Komáromi, Csongor Kiss, Gizella Haramura, Éva Ajzner, Róza Ádány, László Muszbek   +7 more
doaj   +3 more sources

Staged Surgical Palliation for HLHS in a Girl with Severe Factor X Deficiency

The Thoracic & Cardiovascular Surgeon Reports, 2018
Background Factor X deficiency (also known as Stuart–Prower factor deficiency) is an autosomal recessive extremely rare hereditary hematologic disorder, affecting around 1:1,000,000 of the general population.
Ahmed F. Elmahrouk, Mohamed F. Ismail, Abdulbadee Bugis, Nashwa Badawy, Hesham Mohamed Aboelghar, Tamer Hamouda, Ahmed Jamjoom   +6 more
doaj   +2 more sources

PROPHYLAXIS FOR INHERITED DEFICIENCY OF FACTOR X (PROTECT-X): A SYSTEMATIC REVIEW

Hematology, Transfusion and Cell Therapy
Introduction: Hereditary factor X (FX) deficiency (FXD) is a rare autosomal recessive bleeding disorder. The reduced or absent plasma FX clotting activity leads to spontaneous hemorrhages or bleeds after minor trauma. FXD severity varies among mild (FX 6%
VJP Ferreira, AF Costa, RM Camelo
doaj   +2 more sources