Results 41 to 50 of about 1,584,900 (350)
Factor X deficiency: a comment on two recent case studies
The Journal of Haemophilia Practice, 2023 Hereditary factor X deficiency (HFXD) is a rare genetic bleeding disorder, affecting approximately 1 in 1,000,000 individuals globally, and resulting in abnormally low activity of clotting factor X (FX). Diagnosis may occur early in life, particularly in
Branchford Brian
doaj +1 more source
Impact of Rare Bleeding Disorders during Pregnancy on Maternal and Fetal Outcomes: Review of 29 Pregnancies at a Single Center [PDF]
Revista Brasileira de Ginecologia e Obstetrícia, 2017 Objective: This study aims to give information about the relationship between different types of factor deficiencies and maternal/obstetric outcomes. Methods We retrospectively reviewed the medical records of eight women with factor deficiency disorders.
Gokcen Orgul +2 more
doaj +1 more source
Hereditary Factor X (Stuart-Prower Factor) Deficiency [PDF]
Medical Journal Armed Forces India, 2008 Inherited deficiency of Factor X was first reported way back in mid 1950s by workers who were studying patients with a haemorrhagic disease resembling factor VII deficiency. It is also known by the surnames of the patients who were first found to manifest the defect (Stuart and Prower).
P K, Gupta, H, Kumar, S, Kumar
openaire +2 more sources
A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X. [PDF]
, 2008 BackgroundActivated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is
Arruda, VR +7 more
core +2 more sources
The first reported case of factor X deficiency in a Filipino child – case study
The Journal of Haemophilia Practice, 2023 Factor X (FX) deficiency is an extremely rare inherited bleeding disorder affecting one in 1,000,000 people. According to the most recent published census of the World Hemophilia Federation, to date there is no reported case of FX deficiency in the ...
Masacupan Kristian Dorell +3 more
doaj +1 more source
Acquired-Transient Factor X Deficiency in a Teenager with Extensive Burns [PDF]
, 2011 Acquired factor X deficiency is an extremely rare situation. It has shown to be associated with systemic amyloidosis, respiratory mycoplasma infection, factor X inhibitors, antiphospholipid antibodies, vitamin K defi ciency/liver disease as well as the ...
Almeida, T +3 more
core +1 more source
Journal of Thrombosis and Haemostasis, 2020 Congenital factor X deficiency (FXD) is a rare bleeding disorder that often presents with severe bleeding in the neonatal period. Long‐term prophylaxis with infusions of FX‐containing products is recommended in patients with FXD and a personal or family ...
K. Zimowski +5 more
semanticscholar +1 more source
IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells [PDF]
, 2012 The cysteine-type peptidase cathepsin X is highly upregulated in several cancers and presumably promotes tumor invasion through bypassing cellular senescence. Here, we present first evidence that the underlying mechanism may involve the regulation of the
Bunsen, Thea +3 more
core +1 more source
Haematologica, 2008 Due to a homozygous Gly204Arg mutation in the factor X (FX) gene no detectable FX antigen was found in the plasma of a one-year old patient with severe bleeding diathesis.
Zsuzsanna Bereczky +7 more
doaj +1 more source
Undetectable Levels of CSF Amyloid-β Peptide in a Patient with 17β-Hydroxysteroid Dehydrogenase Deficiency [PDF]
, 2011 17β-hydroxysteroid dehydrogenase 10 (HSD10) deficiency is a rare X-linked inborn error of isoleucine catabolism. Although this protein has been genetically implicated in Alzheimer's disease pathogenesis, studies of amyloid-β peptide (Aβ) in patients with
Campistol, Jaume +11 more
core +1 more source