Einstein (São Paulo), 2004 We describe a patient with a prolonged aPTT who was diagnosedas having factor XI deficiency after a rather large hematoma wasformed after angiography.
Jayme Diamant +4 more
doaj +8 more sources
Case Report: Allelic and biallelic variants in coagulation factor XI cause factor XI deficiency [PDF]
Frontiers in Cardiovascular MedicineFactor XI deficiency is a rare inherited coagulation disorder with an estimated prevalence of affecting 1 in 1 million. It is characterized by mild and variable bleeding phenotypes, including bruises, nosebleeds, hematuria, and postpartum hemorrhage.
Chen Liang +9 more
doaj +2 more sources
Identifying the silent deficiency: Severe Factor XI deficiency in an asymptomatic patient with isolated prolonged activated partial thromboplastin time—A case report [PDF]
SAGE Open Medical Case ReportsAssessing a patient with a suspected bleeding disorder is a complex aspect of hematology. Prolonged activated partial thromboplastin time often indicates a coagulation factor deficiency or inhibitor and warrants detailed evaluation. Factor XI deficiency,
Awni Alshurafa +4 more
doaj +2 more sources
One case of surgical treatment of coagulation factor XI deficiency complicated with esophageal cancer: a case report [PDF]
Journal of Cardiothoracic SurgeryBackground Coagulation factor XI deficiency is an autosomal recessive hereditary disease with a low incidence. It usually occurs after surgery or trauma; Esophageal cancer is a common malignant tumor of the digestive tract in China.
Yang Tian +3 more
doaj +2 more sources
A Case Report of Severe Factor XI Deficiency during Cardiac Surgery: Less Can Be More [PDF]
Journal of Cardiovascular Development and Disease, 2022 Severe congenital Factor XI (FXI) deficiency (
Toshinobu Kazui +6 more
doaj +2 more sources
A successful case of laparoscopic colorectal cancer resection in an elderly patient with factor XI deficiency [PDF]
Surgical Case Reports, 2019 Background Congenital XI factor deficiency is a rare disease caused by autosomal recessive inheritance. Clinically, there are few spontaneous hemorrhages, which can cause abnormal bleeding after trauma, surgery, and tooth extraction.
Hiroka Kondo +8 more
doaj +2 more sources
Management of severe factor XI deficiency in pregnancy: A case report [PDF]
SAGE Open Medical Case ReportsFactor XI (FXI) deficiency is one of the rarest coagulation disorders with a frequency of 1:1,000,000. A 30-year-old woman, diagnosed with FXI deficiency at the age of 4, was admitted to our maternity service at 25 weeks of gestation.
Fatima El Hassouni +5 more
doaj +2 more sources
Identification and characterization of factor XI autoantibodies in 2 patients with systemic lupus erythematosus: insights into mechanisms of acquired factor XI deficiency [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: Factor (F)XI is a zymogen that contributes to thrombin generation through activation of FIX. Patients with a complete absence of FXI are prone to developing alloantibody inhibitors after replacement therapy.
Priyanka Srivastava +11 more
doaj +2 more sources
Peri- and Postpartum Management of Patients With Factor XI Deficiency [PDF]
Clinical and Applied Thrombosis/Hemostasis, 2019 Factor XI (FXI) deficiency is an uncommon autosomal disorder with variable bleeding phenotype, making peripartum management challenging. We describe our experience in pregnant women with FXI deficiency and identify strategies to minimize the use of ...
Gloria F. Gerber MD +4 more
doaj +2 more sources
The spectrum of factor XI deficiency in Southeast China: four recurrent variants can explain most of the deficiencies [PDF]
Orphanet Journal of Rare DiseasesBackground Factor XI (FXI) deficiency is an autosomal hemorrhagic disorder characterized by reduced plasma FXI levels. Multiple ancestral variants in the F11 gene have been identified in Ashkenazi Jews and other selected European populations.
Ke Zhang +8 more
doaj +2 more sources