Results 101 to 110 of about 2,411,503 (293)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Biased innovations in the Harrod-Domar model [PDF]
This paper presents an endogenous growth model where the aggre- gate production function is a Leontief (1941) and long run growth is completely explained through biased technological change.
Hernando Zuleta
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Some factors affecting the distribution and apparent abundance of yellowfin and skipjack tuna in the Eastern Pacific Ocean [PDF]
, 1964 ENGLISH: Since 1951, the Inter-American Tropical Tuna Commission has been investigating the biology, ecology and population dynamics of the yellowfin tuna, Thunnus albacares, and the skipjack tuna, Katsuwonus pelamis, in the Eastern Pacific Ocean.
Barrett, Izadore, Broadhead, Gordon C.
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The role of stressful life events and personality on depression among adolescents [PDF]
, 2019 Treball Final de Grau en Psicologia. Codi: PS1048.
Muñoz Rodríguez, Yaiza
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Deserción Estudiantil en la Universidad del Zulia ¿Problema Coyuntural?
Revista Venezolana de Gerencia, 2018 Este artículo se propone describir los factores que causaron la deserción estudiantil en la Universidad del Zulia (LUZ), específicamente en la Facultad de Ciencias Económicas y Sociales (FCES) para el periodo 2011 – 2016.
María C. González +3 more
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