Results 241 to 250 of about 2,447,627 (312)

[Emergency care in Primary Care: A crossed perspective between professionals and citizens. DEMAGUT Study]. [PDF]

Aten Primaria
Trenado-Luengo B, García-Sierra R, Díaz Mondelo E, Torán-Monserrat P.   +3 more
europepmc   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Limitaciones metodológicas del artículo “Factores de riesgo para colecistitis aguda gangrenosa”. [PDF]

Acta Gastroenterol Latinoam
Palomares Rutte JF, Chambi Mejía YC.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

[Comment on the article: "Main clinical factors associated with hypoglycemia in patients with type 2 diabetes"]. [PDF]

Rev Med Inst Mex Seguro Soc
Mendoza-Abarca JE.
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Network analysis of changes in post-migration stressors during treatment for refugees with PTSD. [PDF]

Eur J Psychotraumatol
Bruhn M, Attardo HL, Spiller T, Hjorthøj C, Eplov LF, Carlsson J.   +5 more
europepmc   +1 more source

[Injury and death in motorcyclists: Umbrella review]. [PDF]

Rev Med Inst Mex Seguro Soc
Lugo-Machado JA, Espinoza-Morales DI, Naranjo-Medina ME, Alvídrez-Labrado A, Zazueta-Cárdenas A.   +4 more
europepmc   +1 more source

Temporal behavior of proportional mortality of fetal deaths according to underlying cause, 2011-2020. [PDF]

Rev Esc Enferm USP
Soares de Barros JR, Parenti ABH, Carvalheira APP, Ferrari AP, Duarte MTC, Parada CMGL.   +5 more
europepmc   +1 more source