Results 151 to 160 of about 99,541 (274)
Determinantes contextuales e historia de caries en adultos mayores, Talca, 2016 [PDF]
, 2017 74 p.INTRODUCCIÓN: La caries dental es una de las patologías más prevalentes en el adulto mayor. A pesar que se ha estudiado la etiopatogenia de esta enfermedad, existe escasa evidencia que determine de forma integral la relación entre los factores ...
Quinteros Caceres, María Elisa (Prof. Guía) +2 more
core +1 more source
Nurr1 Orchestrates Claustrum Development and Functionality
Advanced Science, EarlyView.Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan +12 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi +8 more
wiley +1 more source
El constructo de temperamento: Un recorrido desde Hipócrates hasta la psicología moderna [PDF]
, 2012 31 PáginasEl temperamento como constructo de la psicología, ha sido abordado desde diferentes perspectivas (tipologías, dimensiones y perfiles); en el presente documento se hace un recorrido histórico sobre éste concepto, partiendo de Hipócrates hasta ...
Bernal Rueda, Jenny Carolina +1 more
core
A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness
Advanced Science, EarlyView.Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger +17 more
wiley +1 more source
Aportaciones frente a la desmotivación escolar en el nivel de primaria a través del modelo MOCSE [PDF]
, 2017 Treball Final de Grau en Mestre o Mestra d'Educació Primària. Codi: MP1040. Curs acadèmic: 2016/2017The following/present paper has a double objective. On the one hand it pretends to explore the confrontation strategies of how the teachers motivate the ...
Felipe Serrano, María
core
El estudio PISA 2003 en Cataluña : resultados y factores contextuales
, 2006 ESP
openaire +1 more source
Advanced Science, EarlyView.Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi +5 more
wiley +1 more source
Advanced Science, EarlyView.Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang +12 more
wiley +1 more source
, 2011 El propósito de nuestra investigación consiste en analizar cuáles son los factores que determinan el nivel de dedicación de tiempo a actividades voluntarias en trabajadores por cuenta ajena. Para ello se ha aplicado un modelo de regresión logística a una muestra de 6.334 asalariados en el que se consideran cuatro categorías de factores: personales y ...
Ariza Montes, José Antonio +1 more
openaire +1 more source