Results 31 to 40 of about 897,219 (239)
FEBS Open Bio, EarlyView.This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
, 2021 Aprender una segunda lengua o lengua extranjera durante la adolescencia o edad adulta constituye un complejo desafío. Dicha complejidad a menudo resulta en un alto índice de variabilidad sobre los logros, ya que es frecuente encontrarse con que personas ...
Luque, Alicia, Pliatsikas, Christos
core +1 more source
Siglo Cero, 2021 La autodeterminación es una característica disposicional que se pone de manifiesto cuando la persona tiene cierto control sobre su propia vida. Se adquiere a lo largo de la vida en interacción con el entorno, de ahí la importancia de evaluar los factores
Leticia Blázquez Arribas +2 more
doaj +1 more source
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source
Revista Internacional de Sociología, 2011 Se ha hablado mucho de los determinantes institucionales de la justicia transicional (JT). Sin embargo, el conocimiento de qué variables condicionan las actitudes de los ciudadanos ante las políticas de reparación por violaciones de los derechos humanos ...
Paloma Aguilar +2 more
doaj +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Factores contextuales y variables individuales en el ajuste escolar
INFAD, 2014 El objetivo de este estudio es analizar las relaciones entre variables contextuales (apoyo familiar, amistades y profesorado), individuales (autoconcepto y satisfacción con la vida) y el ajuste e implicación escolar.
Lorea Azpiazu, Igor Esnaola, Iker Ros
doaj +1 more source