Results 71 to 80 of about 1,969 (216)

Gestión de la tecnología e innovación: un Modelo de Redes Bayesianas

Economía Teoría y Práctica, 2019
La presente investigación tiene como propósito fundamental estudiar y analizar la gestión de la tecnología e innovación a través de Redes Bayesianas, para lo cual se realiza un modelo en el que se identifican y cuantifican los diversos factores que ...
Antonia Terán Bustamante, Griselda Dávila Aragón, Rosario Castañón Ibarra   +2 more
doaj   +1 more source

Scalable MoS2/Si Photodiode Arrays From Roll‐to‐Roll Mechanical Exfoliation

Advanced Science, EarlyView.
A dry roll‐to‐roll route transforms mechanically exfoliated MoS2 flake networks into silicon‐integrated photodiode arrays. The MoS2/Si junctions generate photovoltaic output without applied bias, allowing illuminated pixels to locate light spots and reconstruct simple images.
Yigit Sozen, Thomas Pucher, Andres Castellanos‐Gomez   +2 more
wiley   +1 more source

From Circuits to Symphonies: A Systems‐Engineering Blueprint for Multimicrobial Synthetic Biology

Advanced Science, EarlyView.
Engineering synthetic microbial consortia requires moving beyond intracellular genetic circuits toward coordinated multicellular design. A modular systems‐engineering framework is presented that integrates communication, temporal coordination, ecological structuring, and predictive modeling to guide application‐dependent consortium design ...
Miguel Fernández‐Niño, Ludger A. Wessjohann, José Manuel Guillamón, Daniela Burgos‐Toro, Silvia Moriano‐Gutiérrez, Giacomo Di Matteo, Zia‐ul Islam, Rinke van van Tatenhove‐Pel, Vanessa Rossetto Marcelino, Rodrigo Ledesma‐Amaro   +9 more
wiley   +1 more source

SPICE‐Compatible Compact Modeling of Cuprate‐Based Memristors Across a Wide Temperature Range

Advanced Electronic Materials, EarlyView.
A physics‐guided compact model for YBCO memristors is introduced, incorporating carrier trapping, field‐induced detrapping, and a differential balance equation to describe their switching dynamics. The model is compared with experiments and implemented in LTspice, allowing realistic circuit‐level simulations.
Thomas Günkel, Aleix Barrera, Lluís Balcells, Narcís Mestres, Enrique Miranda, Anna Palau, Jordi Suñé   +6 more
wiley   +1 more source

Relación teórica entre capacidad de absorción, transferencia del conocimiento e innovación en empresas de servicios

Entramado
La transferencia de conocimiento, la capacidad de absorción y la innovación son factores clave para el éxito de las empresas. El propósito de este artículo es estudiar la relación teórica entre los conceptos: capacidad de absorción, transferencia de ...
Sandra Milena Saavedra-Gutiérrez, Sandra Cristina Riascos-Erazo   +1 more
doaj   +1 more source

Local Order Is Not Enough: Synthetically Accessible Polymers Reveal the Role of Side‐chain Branching Point in Organic Solar Cell and Transistor Performance

Advanced Electronic Materials, EarlyView.
Systematic variation of the side‐chain branching point in a series of donor polymers reveals that moving the branch further from the backbone improves local crystal quality but reduces the overall degree of crystallinity, leading to progressively worse organic solar cell and transistor performance.
Martina Rimmele, Xabier Rodríguez‐Martínez, Zhuoran Qiao, Kaiyang Wei, Adam V. Marsh, Julianna Panidi, Nicola Gasparini, Jaime Martin, Martin Heeney   +8 more
wiley   +1 more source

Innovación Empresarial: Factor de competitividad y calidad de vida en Popayán, Colombia

Revista Venezolana de Gerencia, 2019
En las actuales condiciones competitivas, las micro, pequeñas y medianas empresas de Popayán (Colombia), deben mantener su desarrollo económico en mercados competidos.
María Eugenia Saldarriaga Salazar, María Fernanda Guzmán González, Eduardo Andrés Concha Cerón   +2 more
doaj  

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, EarlyView.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source