Results 121 to 130 of about 13,841,193 (317)
El empleo: factor determinante del desarrollo humano
Bolentín de Coyuntura, 2018 Este artículo surge por la necesidad de analizar la relación del empleo con el Índice de Desarrollo Humano (IDH) en el Ecuador en base a la disponibilidad de datos de fuentes oficiales desde el año 2005 a 2017. Se describe el comportamiento de las variables a lo largo del tiempo y se realiza el análisis econométrico donde se estructuran los modelos ...
Kléber Sinchigalo Guamán +1 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Anales del Sistema Sanitario de Navarra, 2009 Tanto la conducta suicida como el suicidio consumado representan un importante problema de salud pública en todo el mundo, por lo que es importante conocer sus factores determinantes.
E. García de Jalón, V. Peralta
doaj +1 more source
Desigualdad, instituciones e informalidad [PDF]
(Disponible en idioma inglés únicamente) En este trabajo se presentan la teoría y los elementos de prueba de los factores determinantes del tamaño del sector informal. Proponemos un modelo teórico simple en el que el tamaño del sector informal guarda una
Alberto Chong, Mark Gradstein
core
Los determinantes del desarrollo local. Un estudio de caso en Chiapas,México [PDF]
, 2012 Aunque existe consenso a nivel conceptual sobre la importancia del desarrollo local y sus elementos clave, como la potenciación de las capacidades locales y la participación; no lo hay respecto a cómo llevarlo a la práctica.
Diaz Puente, Jose Maria +2 more
core +2 more sources
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Sociodemographic determinants and mortality of premature newborns in a medium and low-income population in Colombia, 2017-2019. [PDF]
Biomedica, 2023 Torres-Muñoz J +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source