Results 61 to 70 of about 770,808 (338)
Background Adherence to adjuvant endocrine therapy (AET) is low in women with breast cancer, which increases the risk of recurrence and mortality. A consistently reported barrier to adherence is low perceived necessity of AET and high concerns.
Samuel G Smith, Sophie M C Green
doaj +1 more source
Antecedentes: la funcionalidad familiar es un importante factor de la salud mental, particularmente en población vulnerable como los adultos mayores. Por lo tanto, es necesario contar con instrumentos de medición válidos, confiables, y equitativos para ...
Noemi E. Iparraguirre Yaurivilca +2 more
doaj +1 more source
A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin +4 more
wiley +1 more source
Análise factorial confirmatória do TEOSQp Confirmatory factorial analysis of TEOSQp
O propósito do presente estudo foi avaliar a confiabilidade, a validade factorial e a invariância (por sexo) da versão portuguesa do TEOSQ (Fonseca & Biddle, 2001). Integraram a amostra 1010 estudantes com uma média de idade de 15,42 anos.
Helder M. Fernandes +1 more
doaj +1 more source
Factorial cumulants reveal interactions in counting statistics
Full counting statistics concerns the stochastic transport of electrons in mesoscopic structures. Recently it has been shown that the charge transport statistics for non-interacting electrons in a two-terminal system is always generalized binomial: it ...
Christian Flindt +11 more
core +1 more source
Compartmentalized Homeostasis Drives High Bamboo Forest Productivity under Nutrient Imbalance
This study reveals how Moso bamboo achieves high productivity despite nutrient‐poor soils. It employs a unique strategy, maintaining strict nutrient balance in its leaves while using woody tissues as flexible storage reservoirs. This compartmentalized mechanism buffers the plant from soil phosphorus limitation and microbial competition, resolving the ...
Zhikang Wang +13 more
wiley +1 more source
A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo +14 more
wiley +1 more source
Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu +20 more
wiley +1 more source
Mother Factory vs. Model Factory
The production systems of Japanese companies are considered to be firm-specific advantages, which lead to superior productivity. The mother factory system, exemplified by Toyota Motor Corporation, has been used as a primary method for transferring Japanese production systems overseas.
openaire +4 more sources
This paper describes the experimental testing of an actuated lower-limb exoskeleton. The exoskeleton is designed to alleviate the loading at the knee joint by supplying assistive torque.
Mervin Chandrapal +4 more
doaj +1 more source

