Results 191 to 200 of about 154,069 (338)

Variational quantum recommendation system with embedded latent vectors. [PDF]

Sci Rep
Debi S, Makmal A.
europepmc   +1 more source

Metagenes and molecular pattern discovery using matrix factorization

Proceedings of the National Academy of Sciences of the United States of America, 2004
Jean-Philippe Brunet, P. Tamayo, T. Golub, J. Mesirov   +3 more
semanticscholar   +1 more source

The factorization of cyclic reduced powers by secondary cohomology operations [PDF]

, 1962
Arunas Liulevicius
openalex   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Multi-layer matrix factorization for cancer subtyping using full and partial multi-omics dataset. [PDF]

Brief Bioinform
Ren Y, Ren F, Yang B.
europepmc   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Localized statistics decoding for quantum low-density parity-check codes. [PDF]

Nat Commun
Hillmann T, Berent L, Quintavalle AO, Eisert J, Wille R, Roffe J.   +5 more
europepmc   +1 more source

THE METHOD OF ODD/EVEN REDUCTION AND FACTORIZATION WITH APPLICATION TO POISSON'S EQUATION.

, 1969
B.L. Buzbee, Gennadii Golub, C. W. Nielson   +2 more
openalex   +2 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

A dynamical systems framework for precision psychiatry. [PDF]

NPJ Digit Med
Bosl WJ, Enlow MB, Nelson CA.
europepmc   +1 more source