Results 121 to 130 of about 6,776,466 (294)

Attention Deficit/Hyperactivity Disorder and Associated Factors Among Children Attending Pediatric Outpatient Departments of West Shewa Zone Public Hospitals, Central Ethiopia

open access: yesPsychology Research and Behavior Management, 2021
Misael Benti, Adamu Birhanu Bayeta, Haji Abu Department of psychiatry Nursing, College of Medicine and Health Sciences Ambo University, Ambo, EthiopiaCorrespondence: Misael BentiAmbo University, P.O.Box:19, Ambo, EthiopiaTel +251938035486Email ...
Benti M, Bayeta AB, Abu H
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Factors associated with severe preeclampsia and eclampsia in Jahun, Nigeria

open access: yes, 2013
Gilles Guerrier,1 Bukola Oluyide,2 Maria Keramarou,1 Rebecca Grais11Epicentre, Paris, France; 2Médecins Sans Frontières, Paris, FranceObjective: To explore traditional herbal medicines as potential risk factors of severe preeclampsia and ...
Keramarou M   +3 more
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Prevalence and factors associated with childhood visual impairment in Ethiopia

open access: yes, 2017
Lidiya Bezabih,1 Tilaye Workneh Abebe,1 Robera Olana Fite2 1Department of Public Health, College of Health Sciences, Adama General Hospital and Medical College, Adama, 2Department of Nursing, College of Medicine and Health Sciences, Wolaita Sodo ...
Abebe TW, Fite RO, Bezabih L
core  

Frequency ofRisk Factors Associated with Road Traffic Accidents of Motorbike in a Big City of a Developing Country

open access: yesJournal of the Dow University of Health Sciences, 2010
Objective: To determine the frequency of risk factors associated with road traffic accidents of motorbike in Karachi, Pakistan. Methods: A descriptive cross-sectional study was carried out in the two tertiary care hospitals (Civil Hospital ...
Arif Ali   +4 more
doaj   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Prevalencia y factores asociados a dermatosis en la población adulta de Honduras, 2017-2018

open access: yesRevista Médica Hondureña
Introduction: In dermatology, there are more than 2,000 entities, some of which affect an individual of any age group at a given moment without distinction of race or sex.
Katia Aguilar Gutiérrez   +6 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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