Results 201 to 210 of about 9,174,632 (257)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Modeling Profitability-Influencing Risk Factors for Construction Projects: A System Dynamics Approach

Buildings, 2022
This study addressed the complexity involved in integrating the causative risk factors influencing construction profitability. Most of the existing studies cover the individual effects of profitability influencing factors.
Muhammad Jamaluddin Thaheem, Badr T Alsulami, Fahim Ullah   +2 more
exaly   +2 more sources

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Factors Influencing Learning and Factors Influencing Persistence

Proceedings of the 2017 International Conference on Information System and Data Mining, 2017
Massive open online courses have opened up access to courses from many highly-regarded universities to learners of diverse backgrounds, such as students, in-service staffs, and senior citizens. This study examined the specific factors that spurred different learners to learn, and the instructional design factors that motivated learners to persist.
Biyun Huang, Khe Foon Hew
openaire   +1 more source

Factors influencing prognosis

Gynecologic Oncology, 1974
Abstract An attempt is made to assess the usual pretreatment information thought to have prognostic significance in adenocarcinoma of the uterine corpus. Clinical impressions from reported series of treated patients plus results of follow-up on a small number of untreated patients were used.
J F, Nolan, P, Morrow, J, Anson
openaire   +2 more sources

Factors Influencing Hospital Resilience

Disaster Medicine and Public Health Preparedness, 2020
ABSTRACTThis study aims at investigating the influencing factors on hospital resilience. For this purpose, a systematic review of the literature was conducted. Six databases, including Web of Science, Scopus, SAGE, EBSCO, Google Scholar, and PubMed were searched for articles published between 2000 and 2018.
Afsaneh, Khademi Jolgehnejad, Reza, Ahmadi Kahnali, ALi, Heyrani   +2 more
openaire   +2 more sources

Analysis of the original influencing factors and secondary influencing factors of academic papers

Library Hi Tech, 2019
Purpose The influencing factors of academic papers have always been the focus of attention in the field of Scientometrics. Exploring the influencing factors of altmetrics indicators and traditional literature indicators on academic papers is beneficial to better explore the potential significance and value of academic papers in the evaluation of ...
Rongying Zhao, Yu Bo
openaire   +1 more source

Factors that Influence Prescribing Decisions

Annals of Pharmacotherapy, 2004
BACKGROUND Strategies to control the quality and cost of medication use are largely dependent on the ability to alter selection of medications. Previous models of prescribing behavior have focused on physicians. In the hospital setting, clinical pharmacists and formulary committee members are also key players in
Glen T, Schumock, Surrey M, Walton, Hayley Y, Park, Edith A, Nutescu, Juan C, Blackburn, Jamie M, Finley, Richard K, Lewis   +6 more
openaire   +2 more sources