Results 171 to 180 of about 5,494,201 (309)

Mean field game model of the impact of reductions in support on faculty research activity. [PDF]

Proc Natl Acad Sci U S A
Brown RA.
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Faculty Senate, Minutes, October 18, 2007

, 2006
1 electronic document. Faculty Senate, Minutes, October 18, 2007. 10 pages.Valdosta State University. Faculty Senate, Minutes, October 18, 2007. Chairperson, Ronald M.
Faculty Senate, Valdosta State University
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Supporting physical activity among students at VSB-TUO

Slovak Journal of Sport Science
The transition to university, particularly during the first year of study, presents students with numerous challenges and changes. One of these is a shift in lifestyle, often accompanied by reduced levels of physical activity. A lack of physical activity
Lukáš Chmelíř, Lukáš Souček, Ondřej Lampa, Václav Šimčík, Šárka Cenková, Roman Vala   +5 more
doaj  

Educator's Blueprint: Optimizing the Resident Research Experience. [PDF]

AEM Educ Train
Gottlieb M, Gawel RJ, Jordan J, Long B, Landry A.   +4 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

AI in UK Medical Education: A Framework for Curriculum Reform. [PDF]

JMIR Med Educ
Gaur A, Kirani Tan J, Sridhar Rao M, Fuad M, Bhatti T, Rishab Bharadwaj H, Mohamed Ahmed KAH.   +6 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Assessment of faculty members' perceptions towards community-oriented health professions education in Egypt: a concurrent convergent mixed-methods study. [PDF]

BMC Med Educ
Hamed O, Mekheimar SI, Abouzeid E, Mustafa SS, Amin MA, Abo-Halawa N, Hassan NH, AlSemeh AE, Talaat W.   +8 more
europepmc   +1 more source