Results 111 to 120 of about 508,363 (252)

RETRACTED: Meligy et al. Therapeutic Potential of Mesenchymal Stem Cells Versus Omega n - 3 Polyunsaturated Fatty Acids on Gentamicin-Induced Cardiac Degeneration. <i>Pharmaceutics</i> 2022, <i>14</i>, 1322. [PDF]

Pharmaceutics
Meligy FY, El-Deen Mohammed HS, Mostafa TM, Elfiky MM, El-Sayed Mohamed Ashry I, Abd-Eldayem AM, Rizk NI, Sabry D, Abd Allah ESH, Ahmed SF.   +9 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Retraction: Molecular docking and <i>in vivo</i>/<i>in vitro</i> studies of a novel thiadiazole Schiff base as a hepatoprotective drug against angiogenesis induced by breast cancer. [PDF]

RSC Adv
Alqahtani NF, Alfaifi MY, Shati A A, Elbehairi SEI, Saleh AM, Kotb ES, Serag WM, Elshaarawy RFM, Alhamdi HW, Hassan YA.   +9 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Correction: Kasem et al. Thymoquinone-Loaded Chitosan Nanoparticles Combat Testicular Aging and Oxidative Stress Through SIRT1/FOXO3a Activation: An In Vivo and In Vitro Study. <i>Pharmaceutics</i> 2025, <i>17</i>, 210. [PDF]

Pharmaceutics
Kasem EA, Hamza G, El-Shafai NM, Ghanem NF, Mahmoud S, Sayed SM, Alshehri MA, Al-Shuraym LA, Ghamry HI, Mahfouz ME, Shukry M.   +10 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

"It's because of me - I made myself get here": First-Generation College Students in STEM Motivations for, and Experiences with, Academic Advising. [PDF]

CBE Life Sci Educ
Forsythe D, Moors AC, Allen Q, Hsu JL.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Corrigendum to "Extracellular matrix remodeling in calcific aortic valve disease: Localized enrichment of type III collagen and LTBP-4" [Matrix Biol Plus 30 (2026) 100194]. [PDF]

Matrix Biol Plus
Kemmochi R, Miyazaki H, Taga Y, Takahashi N, Watanabe T, Ikemura K, Sasaki T, Mizuno K, Hirohata S, Matsumoto M, Oohashi T.   +10 more
europepmc   +1 more source