Results 71 to 80 of about 554,477 (299)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

BIO100: Introduction to General Biology / Faculty of Applied Sciences [PDF]

, 2018
This subject covers an introductory concept of basic biology in the following topics: introduction, biological molecules, cells, plasma membrane and transport of molecules, acquisition of energy by organism, multicellular organization, introduction to ...
UiTM, Faculty of Applied Sciences
core  

Considering Grand Challenges in Biology Education : Rationales and Proposals for Future Investigations to Guide Instruction and Enhance Student Understanding in the Life Sciences [PDF]

, 2018
An international group of biology education researchers offer their views on areas of scholarship that might positively impact our understanding of teaching and learning in biology and potentially inform practices in biology and life science instruction.
McComas, William, Dempster, Edith, Olander, Clas,, Chung Lee, Yeung,, Waarlo, Arend Jan,, McComas, William,, Chung Lee, Yeung, Clément, Pierre, Boerwinkel, Dirk Jan,, Dempster, Edith,, Waarlo, AJ, Reiss, Michael, Olander, Clas, Reiss, MJ, Clément, Pierre,, Clément, P, Reiss, Michael,, Boerwinkel, DJ, Olander, C, McComas, W, Boerwinkel, Dirk Jan, Lee, YC, Waarlo, Arend Jan, Dempster, E   +23 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Biology News, Winter 2014

, 2014
Inside this issue: -- Greetings from the Department of Biology-- Biology Students and Alumni -- Department News -- The Department of Biology receives funding for specimens and microscopes from the Carver Charitable Trust-- Carl Thurman\u27s efforts ...
University of Northern Iowa. Department of Biology.
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Biology News, Spring 2015

, 2015
Inside this issue: -- Greetings from the Department of Biology-- Biology Students and Alumni-- Faculty awards-- Department News-- Biology students travel to University of Kentucky to attend the NCUR Annual Conference-- Tigers Visit UNI Biology Department-
University of Northern Iowa. Department of Biology.
core  

BMS415: Cell Biology and Genetics / Faculty of Applied Sciences [PDF]

, 2022
This course introduces students to the basic concepts of cell biology and genetics. The syllabus includes topics on cell structures and functions, transport and divisions, Mendelism, linkage, crossing over and chromosome mapping, sex chromosome and sex ...
UiTM, Faculty of Applied Sciences
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Faculty perceptions of a professional development program for developing CUREs and promoting inclusive and equitable teaching

Journal of Microbiology & Biology Education
The Diffusion of Innovations (DOI) model can be used to explore how faculty prioritize learning about and adopting new pedagogical approaches. Here, we use the DOI framework to contextualize biology faculty perceptions of a professional development (PD ...
Laura Gough, Rommel Miranda, Matthew Hemm, Leann Norman, Brian Jara   +4 more
doaj   +1 more source