Results 141 to 150 of about 285,743 (339)

Integrative single cell RNA‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objectives Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell‐cell interactions in FAI and hip OA.
Gulzada Kulzhanova, Alexis Klee, Mina Botros, Victoria L. Hansen, John Reuter, Eliya Tazreena Tashbib, Eloise Fadial, Benjamin F. Ricciardi, Brian Giordano, Chia‐Lung Wu   +9 more
wiley   +1 more source

A dancing bear, a colleague, or a sharpened toolbox? The cautious adoption of generative artificial intelligence technologies in digital humanities research

Journal of the Association for Information Science and Technology, EarlyView.
Abstract The emergence of generative artificial intelligence (GenAI) is reshaping the research landscape and carries significant implications for Digital Humanities (DH), a field long intertwined with computational methods and technologies. This study examines how DH scholars are adopting and critically evaluating GenAI in their research. Drawing on an
Rongqian Ma, Meredith Dedema, Andrew Cox
wiley   +1 more source

Immersive reality capabilities of relieving hiraeth

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Understanding how immersive experiences foster a sense of presence sufficient to rival real‐world experiences remains an open research area. Prior work has largely examined episodic memory recall in simulated environments, but less is known about how immersive technologies can reconnect individuals with personal memories.
Erica Mi, Fred Fonseca
wiley   +1 more source

A Novel PPARγ Modulator Falcarindiol Mediates ER Stress-Mediated Apoptosis by Regulating NOX4 and Overcomes Radioresistance in Breast Cancer

Antioxidants
The extract of the rhizome of Cnidium officinale Makino has potential anti-cancer and anti-inflammatory effects in many diseases, such as cancer. However, the biological functions of falcarindiol (FAD) in breast cancer are not fully understood.
Tae Woo Kim, Seong-Gyu Ko
doaj   +1 more source

Field Theory of Disordered Elastic Interfaces at 3-Loop Order: The $\beta$-Function

, 2018
We calculate the effective action for disordered elastic manifolds in the ground state (equilibrium) up to 3-loop order. This yields the renormalization-group $\beta$-function to third order in $\epsilon=4-d$, in an expansion in the dimension $d$ around ...
Doussal, Pierre Le, Husemann, Christoph, Wiese, Kay Joerg   +2 more
core   +4 more sources

Community intermediary strategies and tactics to close digital divides and enhance equitable technology use in everyday life

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Online technologies are required for accessing essential services, such as healthcare, transportation, and education. Challenges to online technology access can prevent resource‐constrained communities from connecting to these services. Human intermediaries who act in the middle space between technology and the person using the technology may ...
Marcy G. Antonio, Alicia Stone, Tawanna Dillahunt, Lorraine Buis, Tiffany C. Veinot   +4 more
wiley   +1 more source

Emotional nourishment begets academic coping during the primary to secondary school transition

British Educational Research Journal, EarlyView.
Abstract The transition from primary to secondary school is widely viewed as the most demanding in a child's educational journey. Despite a wealth of research on this transition, little is known about the children's ‘lived experience’ of it across different contexts.
Peter Wood, Dave Putwain, Pedro Freitas Fernandes   +2 more
wiley   +1 more source

Indirect association between childhood maltreatment and food and alcohol disturbance through insecure attachment in university students

Journal of Eating Disorders
Background Food and Alcohol Disturbance (FAD) is characterized by a functional relationship between disordered eating behaviors and problematic alcohol use.
Ludivine Ritz, Nicolas Mauny, Charlotte Montcharmont, Ninon Dessommes, Denis Jacquet, Maud Lemercier-Dugarin   +5 more
doaj   +1 more source

Humans are not unique: difficult birth is common in placental mammals

Biological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

Symbolic or Substantive Action: Intent, Effort, and Results

Business Strategy and the Environment, EarlyView.
ABSTRACT Many firms have made ambitious climate pledges since the Paris Agreement of 2015. These pledges may be symbolic or substantive, but the literature is fragmented in defining these two terms. We propose a conceptual framework with three frames to delineate symbolic from substantive action: Intent—underlying motivations for engaging in climate ...
Vincent Xinyi Gu, Daniel Charles Matisoff   +1 more
wiley   +1 more source