Results 61 to 70 of about 136,383 (292)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Partial Equalization for MC–CDMA Systems in Non-Ideally Estimated Correlated Fading

, 2010
Multicarrier code-division multiple access (MC–CDMA) can support high data rates in next-generation multiuser wireless communication systems. Partial equalization (PE) is a low-complexity technique for combining the signals of subcarriers to improve the ...
Conti, Andrea, Flavio Zabini, Zabini, Flavio, Andrea Conti, B. M. Masini, Masini, Barbara M, L. Hanzo, F. Zabini, Hanzo, Lajos, Barbara M. Masini, Lajos Hanzo   +10 more
core   +2 more sources

A New Analytical Perspective on Product, Product of Ratio, and Ratio of Product of Lomax Random Variables

IEEE Open Journal of the Communications Society
Various methodologies are proposed in the literature for performance analysis of next-generation communication systems, which generally involve complex analysis.
Puspraj Singh Chauhan, Rahul Maurya, Vimal Bhatia, Faheem A. Khan, Osamah S. Badarneh, Sonia Aissa, Ondrej Krejcar   +6 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Outage Analysis of Mixed FSO/WiMAX Link

IEEE Photonics Journal, 2016
In this paper, we study the outage performance of a complex system consisting of a free-space optical (FSO)/radio-frequency (RF) link. Using radio over free-space optics technology, the FSO link carries Worldwide Interoperability for Microwave Access ...
Nemanja Zdravkovic, Milica I. Petkovic, Goran T. Djordjevic, Kimmo Kansanen   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Relay‐assisted D2D communication over novel multicluster two‐wave and multi‐cluster fluctuating two‐ray channels

IET Networks
A decode and forward relay assisted device‐to‐device (D2D) communications over a novel multicluster two‐wave (MTW) fading is analysed with Terahertz (THz) channel conditions.
Haider Mehdi, Zakir Hussain, Muhammad Junaid Rabbani, Syed Muhammad Atif Saleem, Syed Areeb Ahmed   +4 more
doaj   +1 more source