Results 51 to 60 of about 12,550 (261)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

On the effect of channel fading on greedy scheduling [PDF]

open access: yes2012 Proceedings IEEE INFOCOM, 2012
Greedy Maximal Scheduling (GMS) is an attractive low-complexity scheme for scheduling in wireless networks. Recent work has characterized its throughput for the case when there is no fading/channel variations. This paper aims to understand the effect of channel variations on the relative throughput performance of GMS vis-a-vis that of an optimal ...
Aneesh Reddy   +2 more
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

New spectrum sensing method under time-variant flat fading channels

open access: yesTongxin xuebao, 2014
A dynamic state-space model (DSM) was presented for the problem of spectrum sensing under time-variant flat fading channels (TVFF).The primary user (PU) state and the fading channel were characterized as hidden states.On this basis,a novel method was ...
Meng-wei SUN   +4 more
doaj   +2 more sources

Effect of Mobile Wireless on Outage and BER Performances Over Rician Fading Channel

open access: yesIEEE Access, 2020
Many researchers have analyzed the outage probability of wireless static networks over the Rician fading channel in recent years. However, few researchers consider the mobile wireless network models over the Rician fading channel environment.
Chunxiao Li   +4 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

The Slashed‐Rayleigh Fading Channel Distribution

open access: yesMathematical Problems in Engineering, 2019
We propose an alternative distribution for modelling fading‐shadowing wireless channels. This distribution presents certain advantages over the Rayleigh‐lognormal distribution and the K distribution and has proved useful in the setting described. We obtain closed‐form expressions for the average channel capacity and for the average bit error rate of ...
E. Gómez-Déniz   +2 more
openaire   +3 more sources

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

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