Results 51 to 60 of about 1,274,526 (289)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Secrecy Outage Capacity of Fading Channels [PDF]
IEEE Transactions on Information Theory, 2012 submitted to IEEE Transactions on Information ...
Onur Güngör 0002 +4 more
openaire +4 more sources
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Deconstructing multiantenna fading channels [PDF]
IEEE Transactions on Signal Processing, 2002 Accurate and tractable channel modeling is critical to realizing the full potential of antenna arrays in wireless communications. Current approaches represent two extremes: idealized statistical models representing a rich scattering environment and parameterized physical models that describe realistic scattering environments via the angles and gains ...
openaire +2 more sources
On Backoff in Fading Wireless Channels [PDF]
, 2008 We consider the impact of transmission errors on the backoff algorithm behavior in the IEEE 802.11 protocol. Specifically, since the backoff algorithm assumes that all packet losses are due to collisions, it unnecessarily backs off when a packet is lost due to a transmission error.
Seon-Yeong Han, Nael B. Abu-Ghazaleh
openaire +2 more sources
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
New OSTBC for Blind Channel Estimation and Tracking in MIMO-OFDM Systems
Journal of Telecommunications and Information Technology, 2019 Applying orthogonal space time block coding (OSTBC) to multiple-input multiple-output (MIMO) systems helps reduce receiver complexity. However, this approach has been applied only to flat fading channels, as when the channel is a frequency selective ...
Abdelkader Tami +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Advanced Channel Estimation for MIMO-OFDM in Realistic Channel Conditions
, 2007 An advanced decision-directed channel estimation scheme is proposed, which is suitable for employment in a wide range of multi-antenna multi-carrier systems as well as for communications over the entire range of practical channel conditions.
Akhtman, J. +3 more
core +2 more sources