Results 91 to 100 of about 9,966 (258)

Disproportionality analysis of interstitial lung disease associated with novel antineoplastic agents during breast cancer treatment: a pharmacovigilance studyResearch in context

EClinicalMedicine
Summary: Background: Studies have shown that some antineoplastic agents may be associated with interstitial lung disease (ILD), but large-scale real-world data are lacking.
Zijun Zhu, Yongxin Li, Chaoyong Zhu, Qiuxia Dong, Yixiao Zhang, Zhilin Liu, Dengfeng Ren, Fuxing Zhao, Jiuda Zhao   +8 more
doaj   +1 more source

Aspirin in the Food and Drug Administration Adverse Event Reporting System: Missing Demographics and Underreporting

TH Open, 2017
Background The U.S. Food and Drug Administration (FDA) Adverse Event (AE) Reporting System (FAERS) is a global passive surveillance repository requiring mandatory updates by pharmaceutical manufacturers. Oral antiplatelet agents (OAAs) including aspirin (
Victor L. Serebruany, Ales Tomek, Moo Hyun Kim, Oleg Litvinov, Thomas A. Marciniak   +4 more
doaj   +1 more source

Drug Safety Monitoring in Children: Performance of Signal Detection Algorithms and Impact of Age Stratification [PDF]

, 2016
Introduction: Spontaneous reports of suspected adverse drug reactions (ADRs) can be analyzed to yield additional drug safety evidence for the pediatric population.
Dodd, C.N. (Caitlin), Kaguelidou, F. (Florentia), Osokogu, O.U. (Osemeke), Păcurariu, A.C. (Alexandra), Sturkenboom, M.C.J.M. (Miriam), Weibel, D.M. (Daniel)   +5 more
core   +3 more sources

PCN132 Immune-Related Adverse Events (IRAES) in Melanoma Patients Treated with Programmed Cell Death-1 (PD-1) Inhibitors: An Analysis Using the DATA from FDA Adverse Event Reporting System (FAERS) [PDF]

, 2021
D. Mazumder, A. Lele, R. Tyagi, A. Ghosh
openalex   +1 more source

Comparative Safety Analysis of Avastin and Bevacizumab Biosimilars Based on Food and Drug Administration Adverse Event Reporting System

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 4, October 2025.
ABSTRACT Objective This study aimed to compare adverse event (AE) profiles between Avastin and bevacizumab biosimilars to support clinical decision‐making, given the limited availability of real‐world data. Methods A disproportionality analysis was conducted using the FDA Adverse Event Reporting System (FAERS) to identify and compare AE signals ...
Xiaoyu Zhang, Yupeng Zhang, Xinghang Tang, Li Chen   +3 more
wiley   +1 more source

Broadening the capture of natural products mentioned in FAERS using fuzzy string-matching and a Siamese neural network

Scientific Reports
Increased sales of natural products (NPs) in the US and growing safety concerns highlight the need for NP pharmacovigilance. A challenge for NP pharmacovigilance is ambiguity when referring to NPs in spontaneous reporting systems.
Israel O. Dilán-Pantojas, Tanupat Boonchalermvichien, Sanya B. Taneja, Xiaotong Li, Maryann R. Chapin, Sandra Karcher, Richard D. Boyce   +6 more
doaj   +1 more source

Phase diagram and aggregation dynamics of a monolayer of paramagnetic colloids

, 2017
We have developed a tunable colloidal system and a corresponding simulation model for studying the phase behavior of particles assembling under the influence of long-range magnetic interactions.
Charbonneau, Patrick, Detwiler, Paige, Pham, An T., Socolar, Joshua E. S., Yellen, Benjamin B., Zhuang, Yuan   +5 more
core   +1 more source

Expanding on Abraxane Safety: Temporal Insights and Future Directions for Adverse Event Analysis [Letter]

International Journal of Nanomedicine
Fangcai Yang,1 Wukun Ge2 1Department of Clinical Nutrition, Ninghai First Hospital, Ningbo, Zhejiang, 315600, People’s Republic of China; 2Department of Clinical Pharmacy, Ninghai First Hospital, Ningbo, Zhejiang, 315600, People’s Republic of
Yang F, Ge W
doaj  

Drug-induced interstitial lung disease: a real-world pharmacovigilance study of the FDA Adverse Event Reporting System from 2004 to 2021

Therapeutic Advances in Drug Safety
Background: Drug-induced interstitial lung disease (DILD) is an increasingly common cause of morbidity and mortality. However, due to the lack of specificity, DILD detection remains an unsolved public health challenge.
Tingting Jiang, Hui Su, Jing Xu, Chen Li, Ni Zhang, Yanping Li, Yuanlin Wu, Rui Ni, Yue Ming, Ziwei Li, Li Li, Yao Liu   +11 more
doaj   +1 more source

Safety evaluation of irinotecan: a real-world disproportionality analysis using FAERS and JADER databases during the time period 2004-2024

Frontiers in Pharmacology
IntroductionIrinotecan is a widely used chemotherapeutic agent for treating colorectal, pancreatic, and ovarian cancers. Despite its therapeutic efficacy, the safety profile of irinotecan necessitates continuous pharmacovigilance due to its association ...
Siyu Lou, Huayou Chen, Zhiwei Cui, Xiyuan Zhang, Chengyu Zhu, Linmei Zhou, Yingyong Ou, Fan Zou   +7 more
doaj   +1 more source