Results 91 to 100 of about 9,302 (232)

Semantic Similarity‐Informed Bayesian Borrowing for Quantitative Signal Detection of Adverse Events

Statistics in Medicine, Volume 45, Issue 23-24, October 2026.
ABSTRACT We present a Bayesian dynamic borrowing approach to enhance quantitative identification of adverse events in spontaneous reporting systems. The method embeds a robust meta‐analytic predictive prior and incorporates semantic similarity measures (SSMs) to enable weighted information sharing from clinically similar MedDRA preferred terms (PTs) to
François Haguinet, Jeffery L. Painter, Gregory E. Powell, Andrea Callegaro, Andrew Bate   +4 more
wiley   +1 more source

The top 50 Signal strength of AEs at the PT level ranked by ROR for TXA in FAERS.

The top 50 Signal strength of AEs at the PT level ranked by ROR for TXA in FAERS.
Jing Feng (177843), Chiwei Guo (22569722), Shujuan Zhao (6317975)   +2 more
core   +1 more source

Antipsychotics and Torsadogenic Risk: Signals Emerging from the US FDA Adverse Event Reporting System Database [PDF]

, 2013
Background: Drug-induced torsades de pointes (TdP) and related clinical entities represent a current regulatory and clinical burden. Objective: As part of the FP7 ARITMO (Arrhythmogenic Potential of Drugs) project, we explored the publicly available US ...
MORETTI, Ugo, De Ponti F., Sturkenboom, M.C.J.M. (Miriam), De Ponti, F, Behr, E.R. (Elijah), Koci A, Spina, E, Sturkenboom M, Ariola Koci, Poluzzi E, Spina E, Raschi, E. (Emanuel), Ponti, F. (Fabrizio) de, Ugo Moretti, Spina, E. (Edoardo), Poluzzi, E, POLUZZI, ELISABETTA, Koci, A. (Ariola), Behr ER, Koci, A, Elijah R. Behr, Elisabetta Poluzzi, Poluzzi, E. (Elisabetta), Sturkenboom, MCJM, Moretti, U. (Ugo), Fabrizio De Ponti, KOCI, ARIOLA, Moretti, U, Emanuel Raschi, Raschi, E, Miriam Sturkenboom, DE PONTI, FABRIZIO, Moretti U, RASCHI, EMANUEL, Behr, ER, Raschi E, Edoardo Spina, SPINA, Edoardo, Sturkenboom, M   +38 more
core   +1 more source

Real‐Life Study on Gilteritinib‐Related Infections (GilteRInf): An Italian SEIFEM Study

American Journal of Hematology, Volume 101, Issue 10, Page 2672-2676, October 2026.
Elisa Buzzatti, Irene Terrenato, Martina Tomassi, Federica Lessi, Sara Pezone, Cristina Papayannidis, Gianluca Martini, Fabio Forghieri, Luana Fianchi, Martina Quattrone, Nicola Fracchiolla, Claudio Fozza, Michela Abbenante, Anna Lina Piccioni, Davide Facchinelli, Claudia Maria Basilico, Caterina Buquicchio, Nicola Di Renzo, Monica Piedimonte, Maria Giovanna Cefalo, Daniele Armiento, Adriano Venditti, Alessandro Busca, Francesco Marchesi, Maria Ilaria Del Principe, Livio Pagano   +25 more
wiley   +1 more source

What Is FAER? [PDF]

Anesthesiology, 2011
Denham S, Ward, Carl C, Hug, James R, Zaidan, Alan D, Sessler   +3 more
openaire   +2 more sources

Risk assessment of the top 50 drugs associated with drug-induced orthostatic hypotension: a disproportionality analysis of the FAERS and JADER databases

Scientific Reports
To use the FDA Adverse Event Reporting System (FAERS) database to identify drugs associated with orthostatic hypotension. Adverse event reports of orthostatic hypotension from Q1 2004 to Q3 2024 were obtained from the FAERS and JADER databases.
Gaocan Ren, Xiansu Chi, Pingping Huang, Jinhui Zhang, Yanqiu Ding, Lijun Guo, Qinghua Shang, Xiaochang Ma   +7 more
doaj   +1 more source

Fatal outcome related to drug reaction with eosinophilia and systemic symptoms: a disproportionality analysis of FAERS database and a systematic review of cases

Frontiers in Immunology
BackgroundDrug rash with eosinophilia and systemic symptoms (DRESS) is a life-threatening severe cutaneous adverse reaction.ObjectiveThis study aims to study fatal DRESS cases using FAERS database and systematic review.MethodsData of the FDA Adverse ...
Chunsu Liang, Chunsu Liang, Pengjiao An, Pengjiao An, Yizhou Zhang, Yizhou Zhang, Xin Liu, Xin Liu, Bo Zhang, Bo Zhang   +9 more
doaj   +1 more source

Gabapentinoids-Related Delirium Adverse Events: A Real-World Study from 2004 to 2022 Based on FAERS

Journal of Pain Research
Zhongbiao Nie,1 Cuilv Liang,2 Zhihong Li,1 Xinqiang Han,3 Ran Zhang4 1Department of Pharmacy, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, People’s ...
Nie Z, Liang C, Li Z, Han X, Zhang R
doaj  

TTO analysis of the overall AEs related with TXA and SMQs related to TXA in FAERS.

TTO analysis of the overall AEs related with TXA and SMQs related to TXA in FAERS.
Jing Feng (177843), Chiwei Guo (22569722), Shujuan Zhao (6317975)   +2 more
core   +1 more source

Drug-induced interstitial lung disease: a real-world pharmacovigilance study of the FDA Adverse Event Reporting System from 2004 to 2021

Therapeutic Advances in Drug Safety
Background: Drug-induced interstitial lung disease (DILD) is an increasingly common cause of morbidity and mortality. However, due to the lack of specificity, DILD detection remains an unsolved public health challenge.
Tingting Jiang, Hui Su, Jing Xu, Chen Li, Ni Zhang, Yanping Li, Yuanlin Wu, Rui Ni, Yue Ming, Ziwei Li, Li Li, Yao Liu   +11 more
doaj   +1 more source