Results 241 to 250 of about 15,628 (311)

FDA Adverse Event Reporting System (FAERS) Essentials: A Guide to Understanding, Applying, and Interpreting Adverse Event Data Reported to FAERS

Clinical pharmacology and therapy
The US Food and Drug Administration (FDA) performs safety assessments throughout the life cycle of a drug. Postmarketing safety surveillance promotes the identification of adverse events not known at the time of approval.
Emeri Potter, Melissa Reyes, Jennifer Naples, G. D. Dal Pan   +3 more
semanticscholar   +1 more source

Comprehensive analysis of adverse events associated with onasemnogene abeparvovec (Zolgensma) in spinal muscular atrophy patients: insights from FAERS database

Frontiers in Pharmacology
Onasemnogene Abeparvovec (Zolgensma) is a gene therapy for the treatment of Spinal Muscular Atrophy (SMA) with improved motor neuron function and the potential for a singular treatment.
Wenwen Zhang, Yizhen Yin, Dan Yang, Mengyuan Liu, Caixia Ye, Ruiling Yan, Ruiman Li   +6 more
semanticscholar   +1 more source

Safety of Janus kinase inhibitors in rheumatoid arthritis: a disproportionality analysis using FAERS database from 2012 to 2022

Clinical Rheumatology
Introduction/objective Janus kinase (JAK) inhibitors have expanded treatment options for rheumatoid arthritis (RA), particularly for patients unresponsive to traditional disease-modifying antirheumatic drugs (DMARDs). However, safety concerns necessitate
B. Mikaeili, Zuhair A. Alqahtani, Ana L. Hincapie, Jeff Jianfei Guo   +3 more
semanticscholar   +1 more source

Adverse event reporting of faricimab: a disproportionality analysis of FDA adverse event reporting system (FAERS) database

Frontiers in Pharmacology
Background Faricimab is the first and only bispecific antibody approved by the U.S. Food and Drug Administration (FDA) for intravitreal injection. Given its increasingly widespread use in retinal vascular diseases, understanding its adverse events (AEs ...
Chang-Zhu He, Qin Qiu, Song-Jie Lu, Fu-Li Xue, Jun-Qiao Liu, Yu He   +5 more
semanticscholar   +1 more source

Ocular toxicity associated with anti‐HER2 agents in breast cancer: A pharmacovigilance analysis using the FAERS database

International Journal of Cancer
Anti‐human epidermal growth factor receptor 2 (HER2) agents have exhibited pronounced tumor‐inhibitory activity, yet the accompanying ocular toxicity has frequently been underestimated.
Heng Chen, Guoping Yang, Junlong Ma
semanticscholar   +1 more source

Drug Repurposing Using FDA Adverse Event Reporting System (FAERS) Database.

Current Drug Targets
Drug repurposing is an emerging approach to reassigning existing pre-approved therapies for new indications. The FDA Adverse Event Reporting System (FAERS) is a large database of over 28 million adverse event reports submitted by medical providers ...
Robert Morris, Feng Cheng, Rahinatu Ali
semanticscholar   +1 more source

Analysis and mining of Dupilumab adverse events based on FAERS database

Scientific Reports
This study aims to explore potential adverse events (AEs) related to Dupilumab using data from the US FDA Adverse Event Reporting System (FAERS) database. The FAERS database from Q2 2017 to Q4 2023 was mined for AEs related to Dupilumab. The types of AEs
Hui Gao, Liqiang Cao, Chengying Liu
semanticscholar   +1 more source

Real-world pharmacovigilance study of drug-induced autoimmune hepatitis from the FAERS database

Scientific Reports
This study aims to identify and evaluate the most common drugs associated with the risks of autoimmune hepatitis (AIH) using the FDA Adverse Event Reporting System (FAERS) database.
Bu-kun Zhu, Sida Chen, Xiang Li, Shu-yun Huang, Zhan-yang Luo, Wei Zhang   +5 more
semanticscholar   +1 more source